ENSGALG00000012986


Gallus gallus

Features
Gene ID: ENSGALG00000012986
  
Biological name :KDM5A
  
Synonyms : KDM5A / lysine demethylase 5A
  
Possible biological names infered from orthology : Lysine-specific demethylase 5A / P29375 / Q3UXZ9
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 60300831
Gene end: 60346518
  
Corresponding Affymetrix probe sets: Gga.16739.1.S1_at (Chicken Array)   GgaAffx.24080.1.S1_at (Chicken Array)   GgaAffx.24080.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021168
NCBI entrez gene - 418148     See in Manteia.
RefSeq - XM_004937924
RefSeq - XM_416379
swissprot - F1NN75
Ensembl - ENSGALG00000012986
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KDM5AENSG00000073614Homo sapiens
 Kdm5aENSMUSG00000030180Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KDM5B / Q5F3R2 / Lysine-specific demethylase 5B / Q80Y84* / Q9UGL1* / lysine demethylase 5B*ENSGALG0000003894848
JARID2 / protein Jumonji / Q62315* / Q92833* / jumonji and AT-rich interaction domain containing 2*ENSGALG0000001270211


Protein motifs (from Interpro)
Interpro ID Name
 IPR001606  ARID DNA-binding domain
 IPR001965  Zinc finger, PHD-type
 IPR003347  JmjC domain
 IPR003349  JmjN domain
 IPR004198  Zinc finger, C5HC2-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013637  Lysine-specific demethylase-like domain
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0032922 circadian regulation of gene expression IEA
 biological_processGO:0034720 histone H3-K4 demethylation IEA
 biological_processGO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0051090 regulation of DNA-binding transcription factor activity IEA
 biological_processGO:1901726 negative regulation of histone deacetylase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex IEA
 cellular_componentGO:0032993 protein-DNA complex IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0031490 chromatin DNA binding IEA
 molecular_functionGO:0034647 histone demethylase activity (H3-trimethyl-K4 specific) IEA
 molecular_functionGO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) IEA
 molecular_functionGO:0035064 methylated histone binding IEA
 molecular_functionGO:0042393 histone binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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