ENSGALG00000013183


Gallus gallus

Features
Gene ID: ENSGALG00000013183
  
Biological name :TERT
  
Synonyms : telomerase reverse transcriptase / TERT
  
Possible biological names infered from orthology : O14746 / O70372
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 86021205
Gene end: 86050671
  
Corresponding Affymetrix probe sets: Gga.11755.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021506
Ensembl peptide - ENSGALP00000061829
Ensembl peptide - ENSGALP00000057891
NCBI entrez gene - 420972     See in Manteia.
RefSeq - NM_001031007
RefSeq - XM_015282334
RefSeq Peptide - NP_001026178
swissprot - A0A1L1RSP7
swissprot - A0A1D5PY42
swissprot - F1NMF0
Ensembl - ENSGALG00000013183
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tertENSDARG00000042637Danio rerio
 TERTENSG00000164362Homo sapiens
 TertENSMUSG00000021611Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000477  Reverse transcriptase domain
 IPR003545  Telomerase reverse transcriptase
 IPR021891  Telomerase ribonucleoprotein complex - RNA-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001172 transcription, RNA-templated IEA
 biological_processGO:0006278 RNA-dependent DNA biosynthetic process IEA
 biological_processGO:0007004 telomere maintenance via telomerase IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0022616 DNA strand elongation IEA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IEA
 biological_processGO:0030422 production of siRNA involved in RNA interference IEA
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0032774 RNA biosynthetic process IEA
 biological_processGO:0042635 positive regulation of hair cycle IEA
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity IEA
 biological_processGO:0070200 establishment of protein localization to telomere IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0071897 DNA biosynthetic process IEA
 biological_processGO:0090399 replicative senescence IEA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IEA
 biological_processGO:1903704 negative regulation of production of siRNA involved in RNA interference IEA
 biological_processGO:1904751 positive regulation of protein localization to nucleolus IEA
 biological_processGO:2000648 positive regulation of stem cell proliferation IEA
 biological_processGO:2000773 negative regulation of cellular senescence IEA
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
 cellular_componentGO:0000333 telomerase catalytic core complex IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005697 telomerase holoenzyme complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0031379 RNA-directed RNA polymerase complex IEA
 cellular_componentGO:0042645 mitochondrial nucleoid IEA
 cellular_componentGO:1990572 TERT-RMRP complex IEA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0001223 transcription coactivator binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003720 telomerase activity IEA
 molecular_functionGO:0003721 telomerase RNA reverse transcriptase activity IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003964 RNA-directed DNA polymerase activity IEA
 molecular_functionGO:0003968 RNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0042162 telomeric DNA binding IBA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA
 molecular_functionGO:0051087 chaperone binding IEA
 molecular_functionGO:0070034 telomerase RNA binding IEA
 molecular_functionGO:0098680 template-free RNA nucleotidyltransferase IEA


Pathways (from Reactome)
Pathway description
Telomere Extension By Telomerase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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