ENSGALG00000013726


Gallus gallus

Features
Gene ID: ENSGALG00000013726
  
Biological name :PAICS
  
Synonyms : Multifunctional protein ADE2 Phosphoribosylaminoimidazole-succinocarboxamide synthase Phosphoribosylaminoimidazole carboxylase / P38024 / PAICS
  
Possible biological names infered from orthology : Mus musculus phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase (Paics), transcript variant 5, mRNA. / P22234 / phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase / Q9DCL9
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 65146509
Gene end: 65153878
  
Corresponding Affymetrix probe sets: Gga.3058.1.S1_at (Chicken Array)   GgaAffx.24265.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000022269
Ensembl peptide - ENSGALP00000054840
NCBI entrez gene - 396534     See in Manteia.
RefSeq - XM_015285426
RefSeq - NM_205524
RefSeq Peptide - NP_990855
swissprot - P38024
swissprot - R9PXP8
Ensembl - ENSGALG00000013726
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 paicsENSDARG00000033539Danio rerio
 PAICSENSG00000128050Homo sapiens
 PaicsENSMUSG00000029247Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000031  PurE domain
 IPR018236  SAICAR synthetase, conserved site
 IPR028923  SAICAR synthetase/ADE2, N-terminal
 IPR033626  Class II PurE


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006189 "de novo" IMP biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004638 phosphoribosylaminoimidazole carboxylase activity TAS
 molecular_functionGO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
De novo synthesis of IMP
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000013726 PAICS / P38024 / Multifunctional protein ADE2 Phosphoribosylaminoimidazole-succinocarboxamide synthase Phosphoribosylaminoimidazole carboxylase / P22234* / Q9DCL9* / phosphoribosylaminoimid...  / complex






 

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