ENSMUSG00000029247


Mus musculus

Features
Gene ID: ENSMUSG00000029247
  
Biological name :Paics
  
Synonyms : Mus musculus phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase (Paics), transcript variant 5, mRNA. / Paics / Q9DCL9
  
Possible biological names infered from orthology : P22234 / phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: C3.3
Gene start: 76951307
Gene end: 76967509
  
Corresponding Affymetrix probe sets: 10522668 (MoGene1.0st)   1423564_a_at (Mouse Genome 430 2.0 Array)   1423565_at (Mouse Genome 430 2.0 Array)   1436298_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031160
Ensembl peptide - ENSMUSP00000113483
Ensembl peptide - ENSMUSP00000117027
Ensembl peptide - ENSMUSP00000123558
Ensembl peptide - ENSMUSP00000112879
NCBI entrez gene - 67054     See in Manteia.
MGI - MGI:1914304
RefSeq - XM_017321075
RefSeq - NM_001356974
RefSeq - NM_025939
RefSeq - XM_006535180
RefSeq - XM_006535181
RefSeq - XM_006535182
RefSeq - XM_006535183
RefSeq - XM_006535184
RefSeq - XM_006535185
RefSeq - NM_001356971
RefSeq Peptide - NP_001343903
RefSeq Peptide - NP_080215
RefSeq Peptide - NP_001343900
RefSeq Peptide - NP_001343901
RefSeq Peptide - NP_001343902
swissprot - Q9DCL9
swissprot - D3Z6P1
swissprot - D6RCU8
Ensembl - ENSMUSG00000029247
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 paicsENSDARG00000033539Danio rerio
 PAICSENSGALG00000013726Gallus gallus
 PAICSENSG00000128050Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000031  PurE domain
 IPR018236  SAICAR synthetase, conserved site
 IPR028923  SAICAR synthetase/ADE2, N-terminal
 IPR033626  Class II PurE
 IPR035893  PurE domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006189 "de novo" IMP biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005737 cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004638 phosphoribosylaminoimidazole carboxylase activity IEA
 molecular_functionGO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000029247 Paics / Q9DCL9 / Mus musculus phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase (Paics), transcript variant 5, mRNA. / P22234...  / complex






 

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