Manteia

ENSGALG00000014790

Gallus gallus

Features

Gene ID:	ENSGALG00000014790

Biological name :	CDK7

Synonyms :	CDK7 / cyclin dependent kinase 7

Possible biological names infered from orthology :	P50613 / Q03147

Species:	Gallus gallus

Chr. number:	Z
Strand:	1
Band:
Gene start:	21927643
Gene end:	21950370

Corresponding Affymetrix probe sets:	Gga.9685.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000023830 Ensembl peptide - ENSGALP00000059840 NCBI entrez gene - 771294 See in Manteia. RefSeq - XM_001234586 swissprot - A0A1L1RM47 swissprot - E1C8L2 Ensembl - ENSGALG00000014790

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
CDKL1 / cyclin dependent kinase like 1 / Q00532* / Q8CEQ0*	ENSGALG00000012295	35
CDKL5 / cyclin dependent kinase like 5 / O76039* / Q3UTQ8*	ENSGALG00000016529	32
CDKL2 / cyclin dependent kinase like 2 / Q92772* / Q9QUK0*	ENSGALG00000010119	32

Protein motifs (from Interpro)

Interpro ID	Name
IPR000719	Protein kinase domain
IPR008271	Serine/threonine-protein kinase, active site
IPR011009	Protein kinase-like domain superfamily
IPR017441	Protein kinase, ATP binding site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006366	transcription by RNA polymerase II	IEA
biological_process	GO:0006468	protein phosphorylation	IEA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0050821	protein stabilization	IEA
biological_process	GO:0051726	regulation of cell cycle	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005675	holo TFIIH complex	IEA
cellular_component	GO:0005737	cytoplasm	IBA
cellular_component	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	IEA
cellular_component	GO:0070985	TFIIK complex	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0004672	protein kinase activity	IEA
molecular_function	GO:0004674	protein serine/threonine kinase activity	IEA
molecular_function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	IBA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008022	protein C-terminus binding	IEA
molecular_function	GO:0008094	DNA-dependent ATPase activity	IEA
molecular_function	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	IEA
molecular_function	GO:0016301	kinase activity	IEA

Pathways (from Reactome)

Pathway description

Formation of the Early Elongation Complex

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000015641	CCNH / cyclin H / P51946* / Q61458*	/ complex
ENSGALG00000011910	MNAT1 / MNAT1, CDK activating kinase assembly factor / P51948* / P51949* / CDK-activating kinase assembly factor MAT1 *	/ complex
ENSGALG00000003085	CDK1 / cyclin-dependent kinase 1 / P06493* / P11440*	/ reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr