Manteia

ENSDARG00000051916

Danio rerio

Features

Gene ID:	ENSDARG00000051916

Biological name :	cdk7

Synonyms :	cdk7 / cyclin-dependent kinase 7

Possible biological names infered from orthology :	P50613 / Q03147

Species:	Danio rerio

Chr. number:	5
Strand:	-1
Band:
Gene start:	52000163
Gene end:	52010213

Corresponding Affymetrix probe sets:	Dr.3533.1.S1_at (Zebrafish Array) NM_212961_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000139954 Ensembl peptide - ENSDARP00000051002 Ensembl peptide - ENSDARP00000068117 NCBI entrez gene - 405897 See in Manteia. RefSeq - NM_212961 RefSeq - XM_005165671 RefSeq Peptide - NP_998126 swissprot - Q2V6H0 swissprot - Q6NWC5 swissprot - A0A0R4IXP6 ZFIN ID - ZDB-GENE-010320-2 Ensembl - ENSDARG00000051916

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
cdk20 / A8WIP6 / cyclin-dependent kinase 20 / Q8IZL9* / Q9JHU3*	ENSDARG00000003867	39
cdkl1 / cyclin-dependent kinase-like 1 (CDC2-related kinase) / Q00532* / Q8CEQ0* / cyclin dependent kinase like 1*	ENSDARG00000017329	34
cdkl5 / cyclin-dependent kinase-like 5 / O76039* / Q3UTQ8*	ENSDARG00000015240	32

Protein motifs (from Interpro)

Interpro ID	Name
IPR000719	Protein kinase domain
IPR008271	Serine/threonine-protein kinase, active site
IPR011009	Protein kinase-like domain superfamily
IPR017441	Protein kinase, ATP binding site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006468	protein phosphorylation	IEA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA
biological_process	GO:0051726	regulation of cell cycle	IEA
cellular_component	GO:0005675	holo TFIIH complex	IEA
cellular_component	GO:0005737	cytoplasm	IBA
cellular_component	GO:0070985	TFIIK complex	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0004672	protein kinase activity	IEA
molecular_function	GO:0004674	protein serine/threonine kinase activity	IEA
molecular_function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	IBA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	IEA

Pathways (from Reactome)

Pathway description

Formation of RNA Pol II elongation complex

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000007657	ccnh / cyclin H / P51946* / Q61458*	/ complex
ENSDARG00000002077	mnat1 / MNAT CDK-activating kinase assembly factor 1 / P51949* / P51948* / CDK-activating kinase assembly factor MAT1 * / MNAT1, CDK activating kinase assembly factor*	/ complex
ENSDARG00000101637	ccnd1 / Q90459 / cyclin D1 / P24385* / P25322* / G1/S-specific cyclin-D1 *	/ reaction
ENSDARG00000029018	cdkn1ba / cyclin-dependent kinase inhibitor 1Ba / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*	/ reaction
ENSDARG00000054271	cdkn1bb / cyclin-dependent kinase inhibitor 1Bb / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*	/ reaction
ENSDARG00000026577	cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*	/ reaction
ENSDARG00000076554	cdkn1a / cyclin-dependent kinase inhibitor 1A / P38936* / P39689* / Cyclin-dependent kinase inhibitor 1 *	/ reaction
ENSDARG00000087554	cdk1 / cyclin-dependent kinase 1 / P06493* / P11440*	/ reaction

1 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr