ENSDARG00000007657


Danio rerio

Features
Gene ID: ENSDARG00000007657
  
Biological name :ccnh
  
Synonyms : ccnh / cyclin H
  
Possible biological names infered from orthology : P51946 / Q61458
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 47963940
Gene end: 47975440
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000120229
Ensembl peptide - ENSDARP00000004735
NCBI entrez gene - 541325     See in Manteia.
RefSeq - NM_001013453
RefSeq - XM_005165512
RefSeq Peptide - NP_001013471
swissprot - A2BGI0
ZFIN ID - ZDB-GENE-050320-13
Ensembl - ENSDARG00000007657
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCNHENSGALG00000015641Gallus gallus
 CCNHENSG00000134480Homo sapiens
 CcnhENSMUSG00000021548Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR027081  CyclinH/Ccl1
 IPR031658  Cyclin, C-terminal domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain IBA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0070985 TFIIK complex IEA
 molecular_functionGO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of Incision Complex in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
Cyclin E associated events during G1/S transition
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
RUNX1 regulates transcription of genes involved in differentiation of HSCs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000076554 cdkn1a / cyclin-dependent kinase inhibitor 1A / P38936* / P39689* / Cyclin-dependent kinase inhibitor 1 *  / reaction
 ENSDARG00000087554 cdk1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction
 ENSDARG00000029018 cdkn1ba / cyclin-dependent kinase inhibitor 1Ba / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*  / reaction
 ENSDARG00000101637 ccnd1 / Q90459 / cyclin D1 / P24385* / P25322* / G1/S-specific cyclin-D1 *  / reaction
 ENSDARG00000054271 cdkn1bb / cyclin-dependent kinase inhibitor 1Bb / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*  / reaction
 ENSDARG00000051916 cdk7 / cyclin-dependent kinase 7 / P50613* / Q03147*  / complex
 ENSDARG00000026577 cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*  / reaction
 ENSDARG00000002077 mnat1 / MNAT CDK-activating kinase assembly factor 1 / P51949* / P51948* / CDK-activating kinase assembly factor MAT1 * / MNAT1, CDK activating kinase assembly factor*  / complex






 

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