ENSMUSG00000021548


Mus musculus

Features
Gene ID: ENSMUSG00000021548
  
Biological name :Ccnh
  
Synonyms : Ccnh / Cyclin-H / Q61458
  
Possible biological names infered from orthology : P51946
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: C3
Gene start: 85189408
Gene end: 85223469
  
Corresponding Affymetrix probe sets: 10406482 (MoGene1.0st)   1418584_at (Mouse Genome 430 2.0 Array)   1418585_at (Mouse Genome 430 2.0 Array)   1456293_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022030
Ensembl peptide - ENSMUSP00000130820
Ensembl peptide - ENSMUSP00000130839
Ensembl peptide - ENSMUSP00000131136
Ensembl peptide - ENSMUSP00000129349
NCBI entrez gene - 66671     See in Manteia.
MGI - MGI:1913921
RefSeq - XM_006517325
RefSeq - NM_023243
RefSeq - XM_006517324
RefSeq Peptide - NP_001334516
RefSeq Peptide - NP_075732
swissprot - Q61458
swissprot - F7D1U6
swissprot - E9QA43
swissprot - Q3UUW5
swissprot - E9PWD3
Ensembl - ENSMUSG00000021548
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccnhENSDARG00000007657Danio rerio
 CCNHENSGALG00000015641Gallus gallus
 CCNHENSG00000134480Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR027081  CyclinH/Ccl1
 IPR031658  Cyclin, C-terminal domain 2
 IPR036915  Cyclin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IBA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain IBA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005675 holo TFIIH complex IEA
 cellular_componentGO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex IEA
 cellular_componentGO:0070985 TFIIK complex IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity ISS
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IEA
 molecular_functionGO:0016301 kinase activity IDA
 molecular_functionGO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of Incision Complex in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
Cyclin E associated events during G1/S transition
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
RUNX1 regulates transcription of genes involved in differentiation of HSCs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021103 Mnat1 / P51949 / CDK-activating kinase assembly factor MAT1 / P51948* / MNAT1, CDK activating kinase assembly factor*  / complex
 ENSMUSG00000041431 Ccnb1 / P24860 / G2/mitotic-specific cyclin-B1 / P14635* / cyclin B1*  / reaction
 ENSMUSG00000006728 Cdk4 / P30285 / Cyclin-dependent kinase 4 / P11802*  / reaction
 ENSMUSG00000003031 Cdkn1b / P46414 / Cyclin-dependent kinase inhibitor 1B / P46527*  / reaction
 ENSMUSG00000019942 Cdk1 / P11440 / Cyclin-dependent kinase 1 / P06493*  / reaction
 ENSMUSG00000023067 Cdkn1a / P39689 / Cyclin-dependent kinase inhibitor 1 / P38936* / cyclin dependent kinase inhibitor 1A*  / reaction
 ENSMUSG00000025358 Cdk2 / P97377 / Cyclin-dependent kinase 2 / P24941*  / reaction
 ENSMUSG00000070348 Ccnd1 / P25322 / G1/S-specific cyclin-D1 / P24385* / cyclin D1*  / reaction
 ENSMUSG00000069089 Cdk7 / Q03147 / Cyclin-dependent kinase 7 / P50613*  / complex






 

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