ENSDARG00000002077


Danio rerio

Features
Gene ID: ENSDARG00000002077
  
Biological name :mnat1
  
Synonyms : mnat1 / MNAT CDK-activating kinase assembly factor 1
  
Possible biological names infered from orthology : CDK-activating kinase assembly factor MAT1 / MNAT1, CDK activating kinase assembly factor / P51948 / P51949
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 31648271
Gene end: 31681951
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000027502
NCBI entrez gene - 450080     See in Manteia.
RefSeq - NM_001006100
RefSeq - XM_009307310
RefSeq Peptide - NP_001006100
swissprot - B8A5G8
ZFIN ID - ZDB-GENE-041010-203
Ensembl - ENSDARG00000002077
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MNAT1ENSGALG00000011910Gallus gallus
 MNAT1ENSG00000020426Homo sapiens
 Mnat1ENSMUSG00000021103Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR004575  Cdk-activating kinase assembly factor MAT1/Tfb3
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015877  Cdk-activating kinase assembly factor MAT1, centre
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IBA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 cellular_componentGO:0005675 holo TFIIH complex IBA
 molecular_functionGO:0061575 cyclin-dependent protein serine/threonine kinase activator activity IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of Incision Complex in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
Cyclin E associated events during G1/S transition
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
RUNX1 regulates transcription of genes involved in differentiation of HSCs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000076554 cdkn1a / cyclin-dependent kinase inhibitor 1A / P38936* / P39689* / Cyclin-dependent kinase inhibitor 1 *  / reaction
 ENSDARG00000087554 cdk1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction
 ENSDARG00000101637 ccnd1 / Q90459 / cyclin D1 / P24385* / P25322* / G1/S-specific cyclin-D1 *  / reaction
 ENSDARG00000029018 cdkn1ba / cyclin-dependent kinase inhibitor 1Ba / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*  / reaction
 ENSDARG00000054271 cdkn1bb / cyclin-dependent kinase inhibitor 1Bb / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*  / reaction
 ENSDARG00000051916 cdk7 / cyclin-dependent kinase 7 / P50613* / Q03147*  / complex
 ENSDARG00000007657 ccnh / cyclin H / P51946* / Q61458*  / complex
 ENSDARG00000026577 cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr