ENSGALG00000014924


Gallus gallus

Features
Gene ID: ENSGALG00000014924
  
Biological name :POLQ
  
Synonyms : DNA polymerase theta / POLQ
  
Possible biological names infered from orthology : O75417 / polymerase (DNA directed), theta / Q8CGS6
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 79422423
Gene end: 79478850
  
Corresponding Affymetrix probe sets: Gga.18439.1.S1_s_at (Chicken Array)   GgaAffx.9473.1.S1_s_at (Chicken Array)   GgaAffx.9474.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024026
NCBI entrez gene - 418326     See in Manteia.
RefSeq - XM_416549
swissprot - F1NMU1
Ensembl - ENSGALG00000014924
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polqENSDARG00000044622Danio rerio
 POLQENSG00000051341Homo sapiens
 PolqENSMUSG00000034206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASCC3 / F1NTD6 / Activating signal cointegrator 1 complex subunit 3 ENSGALG0000001546510
POLN / DNA polymerase nu / Q7Z5Q5* / DNA polymerase N*ENSGALG000000156928
HELQ* / Q2VPA6* / Q8TDG4* / helicase, POLQ like*ENSGALG000000112087
HELQ* / Q2VPA6* / Q8TDG4* / helicase, POLQ like*ENSGALG000000432611


Protein motifs (from Interpro)
Interpro ID Name
 IPR001098  DNA-directed DNA polymerase, family A, palm domain
 IPR001650  Helicase, C-terminal
 IPR002298  DNA polymerase A
 IPR011545  DEAD/DEAH box helicase domain
 IPR012337  Ribonuclease H-like superfamily
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR019760  DNA-directed DNA polymerase, family A, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006261 DNA-dependent DNA replication IBA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006284 base-excision repair IEA
 biological_processGO:0006302 double-strand break repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0016446 somatic hypermutation of immunoglobulin genes IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0071897 DNA biosynthetic process IEA
 biological_processGO:0097681 double-strand break repair via alternative nonhomologous end joining IEA
 biological_processGO:2000042 negative regulation of double-strand break repair via homologous recombination IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003887 DNA-directed DNA polymerase activity ISS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0043142 single-stranded DNA-dependent ATPase activity IEA
 molecular_functionGO:0051575 5"-deoxyribose-5-phosphate lyase activity IEA


Pathways (from Reactome)
Pathway description
HDR through MMEJ (alt-NHEJ)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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