ENSDARG00000044622


Danio rerio

Features
Gene ID: ENSDARG00000044622
  
Biological name :polq
  
Synonyms : polq / polymerase (DNA directed), theta
  
Possible biological names infered from orthology : DNA polymerase theta / O75417 / Q8CGS6
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 22851198
Gene end: 22896108
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000065555
Ensembl peptide - ENSDARP00000146335
Ensembl peptide - ENSDARP00000146399
NCBI entrez gene - 566079     See in Manteia.
RefSeq - XM_021473431
RefSeq - XM_009295407
swissprot - F1Q4P4
ZFIN ID - ZDB-GENE-040724-232
Ensembl - ENSDARG00000044622
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLQENSGALG00000014924Gallus gallus
 POLQENSG00000051341Homo sapiens
 PolqENSMUSG00000034206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
helq / helicase, POLQ like / Q2VPA6* / Q8TDG4*ENSDARG0000007981810
snrnp200 / small nuclear ribonucleoprotein 200 (U5) / Q6P4T2* / O75643* / small nuclear ribonucleoprotein U5 subunit 200* / U5 small nuclear ribonucleoprotein 200 kDa helicase *ENSDARG0000007753610
ascc3 / activating signal cointegrator 1 complex subunit 3ENSDARG000000866789
poln / polymerase (DNA directed) nu / Q7Z5Q5* / DNA polymerase N* / DNA polymerase nu*ENSDARG000001039619


Protein motifs (from Interpro)
Interpro ID Name
 IPR001098  DNA-directed DNA polymerase, family A, palm domain
 IPR001650  Helicase, C-terminal
 IPR002298  DNA polymerase A
 IPR011545  DEAD/DEAH box helicase domain
 IPR012337  Ribonuclease H-like superfamily
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR019760  DNA-directed DNA polymerase, family A, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006261 DNA-dependent DNA replication IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
HDR through MMEJ (alt-NHEJ)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism decreased life span , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019529 parp1 / poly (ADP-ribose) polymerase 1 / P09874* / poly (ADP-ribose) polymerase family, member 1*  / reaction / complex
 ENSDARG00000011404 fen1 / Q6TNU4 / flap structure-specific endonuclease 1 / P39748*  / reaction / complex
 ENSDARG00000043480 rbbp8 / F1R983 / retinoblastoma binding protein 8 / Q80YR6* / Q99708* / RB binding protein 8, endonuclease* / retinoblastoma binding protein 8, endonuclease*  / complex / reaction
 ENSDARG00000044622 polq / polymerase (DNA directed), theta / O75417* / Q8CGS6* / DNA polymerase theta*  / complex
 ENSDARG00000040303 nbn / nibrin / Q5I2W8 / O60934* / Q9R207*  / reaction / complex
 ENSDARG00000038917 rad50 / RAD50 homolog, double strand break repair protein / Q92878* / AC116366.3* / RAD50 double strand break repair protein*  / complex / reaction
 ENSDARG00000105014 mre11a / MRE11 homolog A, double strand break repair nuclease / MRE11* / P49959* / MRE11 homolog, double strand break repair nuclease*  / reaction / complex






 

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