ENSGALG00000015143


Gallus gallus

Features
Gene ID: ENSGALG00000015143
  
Biological name :TTR
  
Synonyms : P27731 / Transthyretin / TTR
  
Possible biological names infered from orthology : P02766 / P07309
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 106466187
Gene end: 106475058
  
Corresponding Affymetrix probe sets: Gga.10181.1.S1_at (Chicken Array)   Gga.2620.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000064113
Ensembl peptide - ENSGALP00000024388
NCBI entrez gene - 396277     See in Manteia.
RefSeq - NM_001281498
RefSeq - NM_205335
RefSeq Peptide - NP_001268427
RefSeq Peptide - NP_990666
swissprot - P27731
swissprot - A0A1I7Q422
Ensembl - ENSGALG00000015143
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttrENSDARG00000037191Danio rerio
 TTRENSG00000118271Homo sapiens
 TtrENSMUSG00000061808Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TTR* / P02766* / P07309* / transthyretin*ENSGALG0000004473355
URAH / Q9CRB3* / urate (5-hydroxyiso-) hydrolase*ENSGALG0000000054923


Protein motifs (from Interpro)
Interpro ID Name
 IPR000895  Transthyretin/hydroxyisourate hydrolase
 IPR023416  Transthyretin/hydroxyisourate hydrolase domain
 IPR023418  Transthyretin, thyroxine binding site
 IPR023419  Transthyretin, conserved site
 IPR030178  Transthyretin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001555 oocyte growth IEP
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0042572 retinol metabolic process ISA
 biological_processGO:0051262 protein tetramerization IDA
 biological_processGO:0065003 protein-containing complex assembly IDA
 biological_processGO:0070327 thyroid hormone transport TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISA
 cellular_componentGO:0030136 clathrin-coated vesicle IDA
 cellular_componentGO:0032991 protein-containing complex ISA
 cellular_componentGO:0060417 yolk IDA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0036094 small molecule binding IPI
 molecular_functionGO:0042562 hormone binding ISA
 molecular_functionGO:0046982 protein heterodimerization activity ISA
 molecular_functionGO:0070324 thyroid hormone binding IDA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)
Non-integrin membrane-ECM interactions
Neutrophil degranulation
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001449 STRA6 / stimulated by retinoic acid 6 / Q9BX79* / stimulated by retinoic acid gene 6*  / complex / reaction
 ENSGALG00000006629 RBP4A / P41263 / Retinol-binding protein 4 / RBP4* / Q00724* / P02753*  / reaction / complex
 ENSGALG00000015143 TTR / P27731 / Transthyretin / P02766* / P07309*  / complex






 

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