ENSGALG00000015351


Gallus gallus

Features
Gene ID: ENSGALG00000015351
  
Biological name :CBLB
  
Synonyms : CBLB / Cbl proto-oncogene B
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase CBL-B / Q13191 / Q3TTA7
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 86647126
Gene end: 86769237
  
Corresponding Affymetrix probe sets: GgaAffx.9785.1.S1_at (Chicken Array)   GgaAffx.9785.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024726
NCBI entrez gene - 418406     See in Manteia.
RefSeq - XM_004938278
RefSeq - XM_416621
swissprot - F1NL77
Ensembl - ENSGALG00000015351
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cblbENSDARG00000015199Danio rerio
 CBLBENSG00000114423Homo sapiens
 CblbENSMUSG00000022637Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CBL / E3 ubiquitin-protein ligase CBL / P22681* / P22682* / Cbl proto-oncogene*ENSGALG0000002907749


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001841  Zinc finger, RING-type
 IPR003153  Adaptor protein Cbl, N-terminal helical
 IPR009060  UBA-like superfamily
 IPR011992  EF-hand domain pair
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014741  Adaptor protein Cbl, EF hand-like
 IPR014742  Adaptor protein Cbl, SH2-like domain
 IPR015940  Ubiquitin-associated domain
 IPR017907  Zinc finger, RING-type, conserved site
 IPR024159  Adaptor protein Cbl, PTB domain
 IPR024162  Adaptor protein Cbl


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IBA
 biological_processGO:0007175 negative regulation of epidermal growth factor-activated receptor activity IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0023051 regulation of signaling IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0045121 membrane raft IBA
 molecular_functionGO:0001784 phosphotyrosine residue binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0017124 SH3 domain binding IBA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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