ENSGALG00000015425


Gallus gallus

Features
Gene ID: ENSGALG00000015425
  
Biological name :LPL
  
Synonyms : Lipoprotein lipase / LPL / P11602
  
Possible biological names infered from orthology : P06858 / P11152
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 54528388
Gene end: 54543657
  
Corresponding Affymetrix probe sets: GgaAffx.21769.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036979
NCBI entrez gene - 396219     See in Manteia.
RefSeq - NM_205282
RefSeq - XM_015280414
RefSeq Peptide - NP_990613
swissprot - P11602
Ensembl - ENSGALG00000015425
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FP245456.1ENSDARG00000098720Danio rerio
 lplENSDARG00000087697Danio rerio
 LPLENSG00000175445Homo sapiens
 LplENSMUSG00000015568Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LIPG / lipase G, endothelial type / Q9WVG5* / Q9Y5X9* / Endothelial lipase *ENSGALG0000004373440
LIPC / lipase C, hepatic type / P11150* / P27656* / Hepatic triacylglycerol lipase *ENSGALG0000000423039
PNLIP / P17892* / P54315* / Q6P8U6* / P16233* / Q5BKQ4* / PNLIPRP1* / PNLIPRP2* / pancreatic lipase* / pancreatic lipase related protein 1* / pancreatic lipase-related protein 2* / pancreat...ENSGALG0000000923126
LIPH / lipase H / Q8CIV3* / Q8WWY8* / Lipase member H *ENSGALG0000003860125
LIPI / lipase I / Q6XZB0*ENSGALG0000001566223
PLA1A / phospholipase A1 member A / Q53H76* / Q8VI78*ENSGALG0000001499721
Q17RR3* / PNLIPRP3* / pancreatic lipase related protein 3*ENSGALG0000004524912


Protein motifs (from Interpro)
Interpro ID Name
 IPR000734  Triacylglycerol lipase family
 IPR001024  PLAT/LH2 domain
 IPR002330  Lipoprotein lipase
 IPR013818  Lipase/vitellogenin
 IPR016272  Lipase, LIPH-type
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0010744 positive regulation of macrophage derived foam cell differentiation IEA
 biological_processGO:0010886 positive regulation of cholesterol storage IEA
 biological_processGO:0010890 positive regulation of sequestering of triglyceride IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0019432 triglyceride biosynthetic process IEA
 biological_processGO:0019433 triglyceride catabolic process IEA
 biological_processGO:0034372 very-low-density lipoprotein particle remodeling IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0055096 low-density lipoprotein particle mediated signaling IEA
 biological_processGO:0070328 triglyceride homeostasis IEA
 biological_processGO:0090197 positive regulation of chemokine secretion IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0034361 very-low-density lipoprotein particle IEA
 cellular_componentGO:0042627 chylomicron IEA
 molecular_functionGO:0004465 lipoprotein lipase activity ISS
 molecular_functionGO:0004806 triglyceride lipase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008201 heparin binding ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0034185 apolipoprotein binding IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Assembly of active LPL and LIPC lipase complexes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000015425 LPL / P11602 / Lipoprotein lipase / P06858* / P11152*  / complex






 

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