ENSGALG00000016281


Gallus gallus

Features
Gene ID: ENSGALG00000016281
  
Biological name :DMD
  
Synonyms : DMD / dystrophin
  
Possible biological names infered from orthology : P11531 / P11532
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 114486908
Gene end: 115483002
  
Corresponding Affymetrix probe sets: Gga.718.1.S1_at (Chicken Array)   Gga.718.2.S1_a_at (Chicken Array)   Gga.718.3.S1_at (Chicken Array)   Gga.718.3.S1_a_at (Chicken Array)   Gga.718.3.S1_x_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050332
Ensembl peptide - ENSGALP00000026200
NCBI entrez gene - 396236     See in Manteia.
RefSeq - NM_205299
RefSeq Peptide - NP_990630
swissprot - F1NS97
swissprot - A0A1D5PC47
Ensembl - ENSGALG00000016281
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dmdENSDARG00000008487Danio rerio
 DMDENSG00000198947Homo sapiens
 DmdENSMUSG00000045103Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UTRN / utrophin / P46939*ENSGALG0000001225648
DRP2 / dystrophin related protein 2 / Q05AA6* / Q13474*ENSGALG0000000503113
DTNA / dystrobrevin alpha / Q9D2N4* / Q9Y4J8*ENSGALG000000152115
DYTN / dystrotelin / A2CI98* / A2CJ06*ENSGALG000000085623
DTNB* / O60941* / O70585* / dystrobrevin beta*ENSGALG000000464112
DTNB* / O60941* / O70585* / dystrobrevin beta*ENSGALG000000381911


Protein motifs (from Interpro)
Interpro ID Name
 IPR000433  Zinc finger, ZZ-type
 IPR001202  WW domain
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002017  Spectrin repeat
 IPR011992  EF-hand domain pair
 IPR015153  EF-hand domain, type 1
 IPR015154  EF-hand domain, type 2
 IPR016344  Dystrophin
 IPR018159  Spectrin/alpha-actinin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001954 positive regulation of cell-matrix adhesion IEA
 biological_processGO:0002027 regulation of heart rate IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0007519 skeletal muscle tissue development IEA
 biological_processGO:0008065 establishment of blood-nerve barrier IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IEA
 biological_processGO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion IEA
 biological_processGO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion IEA
 biological_processGO:0014819 regulation of skeletal muscle contraction IEA
 biological_processGO:0014904 myotube cell development IEA
 biological_processGO:0021629 olfactory nerve structural organization IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0034622 cellular protein-containing complex assembly IEA
 biological_processGO:0035994 response to muscle stretch IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0045213 neurotransmitter receptor metabolic process IEA
 biological_processGO:0046716 muscle cell cellular homeostasis IEA
 biological_processGO:0048747 muscle fiber development IEA
 biological_processGO:0051647 nucleus localization IEA
 biological_processGO:0060314 regulation of ryanodine-sensitive calcium-release channel activity IEA
 biological_processGO:0060857 establishment of glial blood-brain barrier IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0086001 cardiac muscle cell action potential IEA
 biological_processGO:1901385 regulation of voltage-gated calcium channel activity IEA
 biological_processGO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation IEA
 biological_processGO:2000651 positive regulation of sodium ion transmembrane transporter activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016010 dystrophin-associated glycoprotein complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030055 cell-substrate junction IEA
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0044306 neuron projection terminus IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0002162 dystroglycan binding IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050998 nitric-oxide synthase binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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