Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000160	kyphosis	"forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0000220	increased monocyte count	"greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cmah^tm1Avrk/Cmah^tm1Avrk,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn
MP:0000222	decreased neutrophil count	"fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx/Y,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn
MP:0000274	enlarged heart	"increase over normal size of the heart" [J:29971]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0000278	abnormal myocardial fiber morphology	"malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0000334	decreased granulocyte number	"fewer than expected number of leukocytes that have abundant granules in the cytoplasm: basophils, neutrophils, or eosinophils" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx/Y,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn
MP:0000462	abnormal digestive system morphology	"anomalous structure of the system dedicated to the mechanical, chemical, and enzymatic processing of food" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA
MP:0000556	abnormal hindlimb morphology	"malformation of the entire posterior extremities" [MGI:tc]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA
MP:0000727	absent CD4-8+ cells	"lack of the set of single-positive T cells that express CD8 on their surface" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17
MP:0000729	abnormal myogenesis	"anomaly in embryonic formation of muscle cells or fibers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0000730	increased number of satellite cells	"greater number of unfused cells in muscle that play a role in muscle regeneration" [J:42574]	Show Allelic Composition: Myf5^tm2Pas/Myf5^tm2Tajb Genetic Background: involves: 129S2/SvPas Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv/J Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺ Genetic Background: involves: C3HA * C57BL/6Ros
MP:0000733	abnormal muscle development	"anomalous differentiation of muscle tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺ Genetic Background: involves: C3HA * C57BL/6Ros Allelic Composition: Cav3^tm1Ncnp/Cav3⁺,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S4/SvJae * C57BL/10 * C57BL/10ScSn
MP:0000745	tremors	"repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ
MP:0000746	weakness	"state of being infirm or less strong than littermates" [J:45400]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn
MP:0000747	muscle weakness	"loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Cmah^tm1Avrk/Cmah^tm1Avrk,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx
MP:0000748	progressive muscle weakness	"increasing loss of strength over time" [MGI:CLS, J:67994]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0000749	muscle degeneration	"pathological deterioration of muscle tissue, often accompanied by loss of function" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^tm1Mok/Y Genetic Background: involves: 129S/SvEv Allelic Composition: Dmd^mdx/Dmd^mdx,Mamstr^tm1.2Eno/Mamstr^tm1.2Eno Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^tm1Kmf/Y Genetic Background: involves: C57BL/6
MP:0000750	abnormal muscle regeneration	"inability or defects in ability to repair muscle after injuries" [J:42574]	Show Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0000751	myopathy	"any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/?,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S4/SvPas * C57BL/6 * C57BL/10ScSn
MP:0000752	dystrophic muscle	"progressive weakness and wasting of muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67994]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/?,Fgf2^tm1Zllr/Fgf2^tm1Zllr,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/? Genetic Background: B6.B10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/?,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S4/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/?,Fgf2^tm1Zllr/Fgf2^tm1Zllr Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Nos1^tm1Plh/Nos1^tm1Plh Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd⁺,Nos1^tm1Plh/Nos1^tm1Plh Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd⁺ Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Cmah^tm1Avrk/Cmah^tm1Avrk,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Dmd^mdx,Dusp1^tm1Brv/Dusp1^tm1Brv Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Tg(ACTA1-SSPN)3.0Rcros/0 Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J Allelic Composition: Ctss^tm1Hap/Ctss^tm1Hap,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S2/SvPas * C57BL/10ScSn Allelic Composition: Dmd^tm1Kmf/Y Genetic Background: involves: C57BL/6 Allelic Composition: Dmd^mdx/Y,Mirc37^tm1Boet/Mirc37^tm1Boet Genetic Background: involves: C57BL/10ScSn
MP:0000759	abnormal skeletal muscle morphology	"anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/?,Fgf2^tm1Zllr/Fgf2^tm1Zllr,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/? Genetic Background: B6.B10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6.Cg-Dmd^mdx-3Cv/J Allelic Composition: Dmd^mdx-4Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv/J Allelic Composition: Dmd^mdx-3Cv/Dmd^mdx-3Cv,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129 * C3H/HeHa * C57BL * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx-3Cv/Y,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129 * C3H/HeHa * C57BL * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL
MP:0000761	thin diaphragm muscle	"reduced thickness of the diaphragm muscle" [MGI:CLS, J:60159]	Show Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0001053	abnormal neuromuscular synapse	"malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn
MP:0001260	increased body weight	"greater than normal average weight " [J:33400]	Show Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺ Genetic Background: involves: C3HA * C57BL/6Ros Allelic Composition: Dmd^tm1Kmf/Y Genetic Background: involves: C57BL/6
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv Allelic Composition: Dmd^mdx/Dmd^mdx,Dusp1^tm1Brv/Dusp1^tm1Brv Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Mamstr^tm1.2Eno/Mamstr^tm1.2Eno Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx
MP:0001263	weight loss	"progressive reduction of body weight below normal average for age" [J:45400]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA
MP:0001264	increased body size	"larger than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]	Show Allelic Composition: Dtna^tm1Jrs/Dtna^tm1Jrs,Dtnb^{Gt(OST109050)Lex}/Dtnb^{Gt(OST109050)Lex} Genetic Background: involves: 129S5/SvEvBrd * 129X1/SvJ * C57BL/6
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA Allelic Composition: Dmd^mdx/Dmd⁺,Foxk1^tm1Djg/Foxk1⁺ Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Dusp1^tm1Brv/Dusp1^tm1Brv Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0001402	hypoactivity	"reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx/Dmd^mdx,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0001405	impaired coordination	"reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv Allelic Composition: Cmah^tm1Avrk/Cmah^tm1Avrk,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv Allelic Composition: Cmah^tm1Avrk/Cmah^tm1Avrk,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0001407	short stride length	"reduced average distance between steps" [J:34193]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv
MP:0001504	abnormal posture	"atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA
MP:0001515	abnormal grip strength	"altered ability to grasp and hold objects, usually measured as time spent hanging from an object or wire" [J:80661]	Show Allelic Composition: Dtna^tm1Jrs/Dtna^tm1Jrs,Dtnb^{Gt(OST109050)Lex}/Dtnb^{Gt(OST109050)Lex} Genetic Background: involves: 129S5/SvEvBrd * 129X1/SvJ * C57BL/6 Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6.Cg-Dmd^mdx-3Cv/J Allelic Composition: Dmd^mdx-4Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv/J
MP:0001661	extended life span	"persistence of life for a longer period than is the norm for an organism" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺ Genetic Background: involves: C3HA * C57BL/6Ros
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn
MP:0001853	heart inflammation	"local accumulation of fluid, plasma proteins, and leukocytes in the heart" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0001856	myocarditis	"inflammation of the heart walls" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Prnp^tm1Cwe/Prnp^tm1Cwe,Tg(PrnpS170NN174T)1020Aag/0 Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
MP:0001921	reduced fertility	"diminished ability to produce live offspring" [J:65030]	Show Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-2Cv Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17
MP:0001923	reduced female fertility	"reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd
MP:0001925	male infertility	"inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Dmd^tm1Khan/Dmd^tm1Khan Genetic Background: involves: C57BL/6 * CBA
MP:0001935	reduced litter size	"fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx-3Cv/Dmd^mdx-3Cv Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv
MP:0001951	abnormal breathing	"irregular or atypical breathing pattern " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA
MP:0001953	respiratory failure	"cessation of or failure to commence breathing" [MGI:cls, J:60159]	Show Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL
MP:0002066	abnormal motor capabilities/coordination/movement	"altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/?,Myod1^tm1Jae/Myod1^tm1Jae Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Cmah^tm1Avrk/Cmah^tm1Avrk,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0002106	abnormal muscle physiology	"anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^{Gt(ROSABetageo)1Mpd}/Y Genetic Background: involves: 129S1/Sv Allelic Composition: Dmd^{Gt(ROSABetageo)1Mpd}/Dmd^{Gt(ROSABetageo)1Mpd} Genetic Background: involves: 129S1/Sv Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/?,Fgf2^tm1Zllr/Fgf2^tm1Zllr,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Mmp9^tm1Tvu/Mmp9⁺ Genetic Background: B10.Cg-Mmp9^tm1Tvu Dmd^mdx Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc⁺ Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL
MP:0002108	abnormal muscle morphology	"abnormal development of muscle tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^{Gt(ROSABetageo)1Mpd}/Y Genetic Background: involves: 129S1/Sv Allelic Composition: Dmd^{Gt(ROSABetageo)1Mpd}/Dmd^{Gt(ROSABetageo)1Mpd} Genetic Background: involves: 129S1/Sv Allelic Composition: Dmd^mdx/Dmd^mdx,Mmp9^tm1Tvu/Mmp9^tm1Tvu Genetic Background: B10.Cg-Mmp9^tm1Tvu Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx,Mmp9^tm1Tvu/Mmp9⁺ Genetic Background: B10.Cg-Mmp9^tm1Tvu Dmd^mdx Allelic Composition: Dmd^mdx/Y,Foxn1^nu/Foxn1^nu Genetic Background: involves: C57BL/10ScSn
MP:0002109	abnormal limb morphology	"abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn
MP:0002127	abnormal cardiovascular system morphology	"abnormal development of the heart or vascular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^{Gt(ROSABetageo)1Mpd}/Dmd^{Gt(ROSABetageo)1Mpd} Genetic Background: involves: 129S1/Sv
MP:0002128	abnormal blood circulation	"failure or atypical movement in the flow of blood from the heart to the vasculature and back to the heart" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺ Genetic Background: involves: C3HA * C57BL/6Ros
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Hprt^b-m3/Y,Impdh2^tm1Bmi/Impdh2⁺ Genetic Background: involves: 129P2/OlaHsd Allelic Composition: Dmd^tm1Khan/Dmd^tm1Khan Genetic Background: involves: C57BL/6 * CBA
MP:0002269	muscular atrophy	"a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL
MP:0002279	abnormal diaphragm morphology	"structural defect in the thin musculomebraneous barrier that separates the abdominal and thoracic cavities; these muscles often used for breathing control" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/?,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S4/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^tm1Mok/Y Genetic Background: involves: 129S/SvEv Allelic Composition: Dmd^mdx-2Cv/Dmd^mdx-2Cv Genetic Background: B6Ros.Cg-Dmd^mdx-2Cv Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-2Cv Allelic Composition: Dmd^mdx-3Cv/Dmd^mdx-3Cv Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv Allelic Composition: Dmd^mdx-4Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc⁺ Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0002280	abnormal intercostal muscle morphology	"anomaly in the respiratory muscles that arise from the lower border of one rib and insert into the upper border of the adjoining rib " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Cav3^tm1Ncnp/Cav3⁺,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S4/SvJae * C57BL/10 * C57BL/10ScSn
MP:0002410	decreased susceptibility to viral infection	"reduced likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Prnp^tm1Cwe/Prnp^tm1Cwe,Tg(PrnpS170NN174T)1020Aag/0 Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
MP:0002753	dilated left ventricle	"an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0002795	dilated cardiomyopathy	"decreased function of the heart associated with cardiac enlargement and congestive heart failure" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Dmd^mdx/?,Myod1^tm1Jae/Myod1^tm1Jae Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0002833	increased heart weight	"greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]	Show Allelic Composition: Dmd^mdx/?,Myod1^tm1Jae/Myod1^tm1Jae Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn
MP:0002837	dystrophic cardiac calcinosis	"a condition characterized by the localized deposition of calcium salts in the heart; often occuring in association with inflammation or atherosclerotic lesions and other pathological states" [J:76777, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0002841	impaired skeletal muscle contractility	"inability or reduced ability of the skeletal muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0002899	fatigue	"easily exhausted due to mental or physical exertion" [hdene:Howard Dene , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv
MP:0002952	ventricular cardiomyopathy	"diseases of the ventricles of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0002953	thick ventricular wall	"increased depth of the cardiac wall of the heart ventricles" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0003061	decreased aerobic running capacity	"reduced ability to run at defined speeds and/or distances compared to controls" [RGD:Rat Genome Database submission]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx
MP:0003084	abnormal skeletal muscle fiber morphology	"anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/?,Fgf2^tm1Zllr/Fgf2^tm1Zllr,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/? Genetic Background: B6.B10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd⁺ Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺ Genetic Background: involves: C3HA * C57BL/6Ros Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J Allelic Composition: Ctss^tm1Hap/Ctss^tm1Hap,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S2/SvPas * C57BL/10ScSn
MP:0003105	abnormal heart atrium morphology	"structural anomaly of one or both of the two upper chambers of the heart " [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0003141	cardiac fibrosis	"formation of fibrous tissue within the heart often resulting from inflammation or injury " [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/?,Myod1^tm1Jae/Myod1^tm1Jae Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv Allelic Composition: Dmd^tm1.1Know/Dmd^tm1.1Know,Tg(Myh6-2A)#Know/0,A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/0 Genetic Background:* involves: BALB/c * C3H * C57BL/6 * FVB/N
MP:0003155	abnormal telomere length	"abnormal length of the terminal section of a chromosome which has a specialized structure and which is involved in chromosomal replication and stability; normal length is a few hundred base pairs" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, hdene:Howard Dene , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0003157	impaired muscle relaxation	"reduced or absent ability of muscle to lengthen following contractions" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92510]	Show Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0003199	muscle calcification	"pathologic deposition of calcium salts in muscle" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0003358	abnormal hypaxial muscle morphology	"malformation of the muscles of the limbs" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/?,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S4/SvPas * C57BL/6 * C57BL/10ScSn
MP:0003393	decreased cardiac output	"reduction in the blood volume pumped by each ventricle per minute" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0003646	muscle fatigue	"increased muscle exhaustion or increased susceptibility to muscle exhaustion" [J:96306]	Show Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv
MP:0003674	oxidative stress	"condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0003790	absent CD4+8- cells	"lack of the set of single-positive T cells that express CD4 on their surface" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, acv:Alicia Valenzuela, Genetic Resources Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17
MP:0003833	decreased number of satellite cells	"less than the normal number of unfused cells in muscle that play a role in muscle regeneration" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/?,Fgf2^tm1Zllr/Fgf2^tm1Zllr,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL
MP:0003851	skeletal muscle interstitial fibrosis	"formation of fibrous tissue within the interstices of skeletal muscle as a result of repair or a reactive process" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA
MP:0003852	skeletal muscle necrosis	"pathological cell death in the skeletal muscle, usually due to irreversible damage" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd⁺,Foxk1^tm1Djg/Foxk1⁺ Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL
MP:0003884	decreased macrophage count	"fewer than the normal numbers of macrophages" [acv:Alicia Valenzuela, Genetic Resources Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Mmp9^tm1Tvu/Mmp9^tm1Tvu Genetic Background: B10.Cg-Mmp9^tm1Tvu Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx,Mmp9^tm1Tvu/Mmp9⁺ Genetic Background: B10.Cg-Mmp9^tm1Tvu Dmd^mdx
MP:0003950	abnormal plasma membrane morphology	"anomalous structure of the semipermeable membrane that encloses the cytoplasm of a cell" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Apc^Min/Apc^Min,Rr27^tm1Rohl/Rr27⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J Allelic Composition: Dmd^tm1Mok/Y Genetic Background: involves: 129S/SvEv
MP:0004036	abnormal muscle relaxation	"altered ability of the muscle to lengthen following contractions" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn
MP:0004071	prolonged P wave	"increase in the length of time of the P wave electrical impulses" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv/J
MP:0004087	abnormal muscle fiber morphology	"malformed or poorly developed muscle fibers, the cylindrical multinucleated muscle cells that contract when stimulated" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Cav3^tm1Ncnp/Cav3⁺,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S4/SvJae * C57BL/10 * C57BL/10ScSn
MP:0004089	dilated sarcoplasmic reticulum	"an expansion in the volume in the endoplasmic reticulum of skeletal and cardiac muscle, i.e. the complex of vesicles, tubules, and cisternae that form a continuous structure around striated myofibrils, with a repetition of structure within each sarcomere" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn
MP:0004121	abnormal sarcolemma morphology	"structural anomaly in the plasma membrane of a muscle fiber that is cabable of conducting electrical impuses" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Tg(ACTA1-SSPN)3.0Rcros/0 Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^tm1.1Know/Dmd^tm1.1Know Genetic Background: involves: C3H
MP:0004142	abnormal muscle tone	"anomaly in the resting tautness or laxity of a muscle, normally somewhere in the middle of the range between total contraction and total relaxation" [hdene:Howard Dene , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn
MP:0004145	abnormal muscle electrophysiology	"anomaly in the function of the musculature as it relates to electrical phenomena" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL
MP:0004174	abnormal spine curvature	"deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx/?,Fgf2^tm1Zllr/Fgf2^tm1Zllr,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/?,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S4/SvPas * C57BL/6 * C57BL/10ScSn
MP:0004215	abnormal myocardial fiber physiology	"anomaly in the function of the multinucleated muscle cells of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv/J
MP:0004232	decreased muscle weight	"less than average muscle weight" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0004248	abnormal epaxial muscle morphology	"any structural anomaly of the muscles derived from the medial myotome; includes the intrinsic back muscles" [PMID:1591996]	Show Allelic Composition: Dmd^mdx/?,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S4/SvPas * C57BL/6 * C57BL/10ScSn
MP:0004262	abnormal physical strength	"altered ability of an organism to exert force on physical objects or of the body to support its load" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Y,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn
MP:0004510	myositis	"inflammation of skeletal muscle; local accumulation of fluid, plasma proteins, and leukocytes in the striated muscle" [MESH:C05.651.594]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Dmd^mdx,Dusp1^tm1Brv/Dusp1^tm1Brv Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y,Utrn^tm1Jrs/Utrn⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^tm1Kmf/Y Genetic Background: involves: C57BL/6
MP:0004564	enlarged myocardial fiber	"increased size of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/?,Myod1^tm1Jae/Myod1^tm1Jae Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn
MP:0004566	myocardial fiber degeneration	"deterioration or destruction of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0004597	increased susceptibility to noise-induced hearing loss	"greater than normal reduction in hearing sensitivity following exposure to acute noise that is injurious to the cochlea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0004703	abnormal vertebral column	"any structural anomaly of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn * CB17
MP:0004818	increased skeletal muscle mass	"increase in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn
MP:0004819	decreased skeletal muscle mass	"reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0004973	increased regulatory T cell number	"greater number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Y,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn
MP:0005015	increased T cell number	"greater than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx/Y,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn
MP:0005017	decreased B cell number	"fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17
MP:0005018	decreased T cell number	"fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx/Y,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Spp1^tm1Blh/Spp1^tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn
MP:0005137	increased growth hormone level	"greater than the expected concentration of the hormone that promotes body growth, fat mobilization, and inhibition of glucose utilization" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0005140	decreased cardiac muscle contractility	"inability or reduced ability of the heart muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0005165	increased susceptibility to injury	"greater than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Sh2d1a^tm1Pls/Sh2d1a^tm1Pls,Tg(TcraTcrb)1100Mjb/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Dag1^tm1.1Swin/Dag1^tm1.1Swin,Dmd^mdx/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/10ScSn
MP:0005166	decreased susceptiblity to injury	"less than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^tm1.1Know/Dmd^tm1.1Know Genetic Background: involves: C3H
MP:0005294	abnormal heart ventricle morphology	"structural anomaly of one or both of the two lower chambers of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Dmd^mdx/?,Myod1^tm1Jae/Myod1^tm1Jae Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn
MP:0005330	cardiomyopathy	"diseases of the heart (myocardium); may result from many causes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:80681]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^tm1.1Know/Dmd^tm1.1Know,Tg(Myh6-2A)#Know/0,A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/0 Genetic Background:* involves: BALB/c * C3H * C57BL/6 * FVB/N Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0005425	increased macrophage count	"greater than the normal numbers of macrophages" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:73418]	Show Allelic Composition: Cmah^tm1Avrk/Cmah^tm1Avrk,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn
MP:0005547	abnormal Muller cell morphology	"anomalous structure of the elongated neuroglial cells that traverse all the layers of the retina and that act as supporting elements" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-2Cv/J Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6.Cg-Dmd^mdx-3Cv/J
MP:0005551	abnormal eye electrophysiology	"abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]	Show Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-2Cv/J Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6.Cg-Dmd^mdx-3Cv/J Allelic Composition: Dmd^mdx-4Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv/J
MP:0005598	decreased ventricle muscle contractility	"reduced ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0005599	increased cardiac muscle contractility	"greater than the normal ability of the heart muscle to shorten or to develop increased tension " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Dmd^tm1.1Know/Dmd^tm1.1Know,Tg(Myh6-2A)#Know/0,A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/0 Genetic Background:* involves: BALB/c * C3H * C57BL/6 * FVB/N
MP:0005608	cardiac interstitial fibrosis	"formation of fibrous tissue within the interstices of the heart as a result of repair or a reactive process" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Dmd^mdx/?,Myod1^tm1Jae/Myod1^tm1Jae Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn
MP:0005620	abnormal muscle contractility	"aberrant ability of a muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6.Cg-Dmd^mdx-3Cv/J Allelic Composition: Dmd^mdx-4Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv/J Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv/J Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺ Genetic Background: involves: C3HA * C57BL/6Ros
MP:0006085	myocardial necrosis	"pathological cell death of the cardiac muscle cells, usually due to irreversible damage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92722]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/?,Myod1^tm1Jae/Myod1^tm1Jae Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0006190	retinal ischemia	"abnormal incidence of or response to loss of circulation in the retina; may be induced or spontaneous" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv/J
MP:0008327	abnormal corticotroph morphology	"any structural anomaly of an anterior pituitary basophilic cell that produces adrenocorticotrophic hormone (ACTH)" [CL:0000467, MESH:A06.407.747.608.500]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0008416	increased somatotroph cell size	"excessive growth or enlargement of an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin" [MESH:A06.407.747.608.937, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0008560	increased tumor necrosis factor secretion	"increase in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0008566	increased interferon-gamma secretion	"increase in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0008663	increased interleukin-12 secretion	"increase in the production or release of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells and plays a role in the stimulation of interferon-gamma production by T-cells and natural killer cells" [MESH:D12.644.276.374.465.512]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0008687	increased interleukin-2 secretion	"increase in the production or release of a soluble substance elaborated by antigen- or mitogen-stimulated T-cells which induces DNA synthesis in naive lymphocytes" [MESH:D12.644.276.374.465.502]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0008699	increased interleukin-4 secretion	"increase in the production or release of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells" [MESH:D12.644.276.374.465.504]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0008705	increased interleukin-6 secretion	"increase in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts" [MESH:D12.644.276.374.465.506]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0008837	increased transforming growth factor level	"greater concentration of a paracrine growth factor that has a potential role in embryonic development, cellular differentiation, hormone secretion, and immune function" [MESH:D12.644.276.374.687]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn * CB17
MP:0008838	decreased transforming growth factor level	"reduced concentration of a paracrine growth factor that has a potential role in embryonic development, cellular differentiation, hormone secretion, and immune function" [MESH:D12.644.276.374.687]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17
MP:0008866	chromosomal instability	"abnormalities of DNA metabolism, DNA repair, cell-cycle governance, or control of apoptosis that increase the probability that whole chromosomes or pieces of chromosomes are gained or lost during cell division, resulting in an imbalance in the number of chromosomes per cell (aneuploidy) and an enhanced rate of loss of heterozygosity" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:12446840]	Show Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL
MP:0008874	decreased sensitivity to xenobiotics	"increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn
MP:0009398	abnormal skeletal muscle fiber size	"anomaly in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺ Genetic Background: involves: C3HA * C57BL/6Ros
MP:0009399	increased skeletal muscle fiber size	"increase in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^tm1Khan/Dmd^tm1Khan Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Dmd^mdx/Y,Foxn1^nu/Foxn1^nu Genetic Background: involves: C57BL/10ScSn
MP:0009400	decreased skeletal muscle fiber size	"decrease in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Dusp1^tm1Brv/Dusp1^tm1Brv Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Foxn1^nu/Foxn1^nu Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0009401	increased skeletal muscle fiber diameter	"increased width of the cross-sectional distance that extends from one lateral edge of a skeletal muscle fiber, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Myf5^tm2Tajb/Myf5^tm2Tajb Genetic Background: involves: 129S2/SvPas * C3H/HeHa * C57BL * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn * CB17
MP:0009402	decreased skeletal muscle fiber diameter	"decreased width of the cross-sectional distance that extends from one lateral edge of a skeletal muscle fiber, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Dusp1^tm1Brv/Dusp1^tm1Brv Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0009403	increased variability of skeletal muscle fiber size	"greater range or dispersion within a distribution of skeletal muscle fiber size within a muscle compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/?,Fgf2^tm1Zllr/Fgf2^tm1Zllr,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx-3Cv/Dmd^mdx-3Cv Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6.Cg-Dmd^mdx-3Cv/J Allelic Composition: Dmd^mdx-4Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv/J Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv/J Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0009404	centrally nucleated skeletal muscle fibers	"cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Utrn^tm1Ked/Utrn^tm1Ked Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10ScSn * DBA Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-3Cv/Dmd^mdx-3Cv Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6.Cg-Dmd^mdx-3Cv/J Allelic Composition: Dmd^mdx-4Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv/J Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv/J Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3HA * C57BL/6Ros Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc⁺ Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Dmd^mdx,Tg(ACTA1-SSPN)3.0Rcros/0 Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dag1^tm1.1Swin/Dag1^tm1.1Swin,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/10ScSn Allelic Composition: Dag1^tm1.1Swin/Dag1^tm1.1Swin,Dmd^mdx/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J Allelic Composition: Ctss^tm1Hap/Ctss^tm1Hap,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S2/SvPas * C57BL/10ScSn Allelic Composition: Cav3^tm1Ncnp/Cav3⁺,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S4/SvJae * C57BL/10 * C57BL/10ScSn
MP:0009405	increased skeletal muscle fiber number	"increased number of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0009406	decreased skeletal muscle fiber number	"decreased number of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx
MP:0009410	abnormal skeletal muscle satellite cell proliferation	"anomaly in the ability of unfused cells in skeltal muscle to undergo expansion by cell division, usually triggered by injury or disease" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Mamstr^tm1.2Eno/Mamstr^tm1.2Eno Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0009412	skeletal muscle fiber degeneration	"pathological deterioration of skeletal muscle fiber tissue, often accompanied by loss of function" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^tm1Khan/Dmd^tm1Khan Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx,Dusp1^tm1Brv/Dusp1^tm1Brv Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn * CB17
MP:0009413	skeletal muscle fiber atrophy	"a wasting of skeletal muscle fibers resulting in a derangement of the skeletal muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0009414	skeletal muscle fiber necrosis	"pathological cell death in the skeletal muscle fibers, usually due to irreversible damage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^tm1.1Khan/Y Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Dmd^mdx/?,Fgf2^tm1Zllr/Fgf2^tm1Zllr,Fgf6^tm1Thbr/Fgf6^tm1Thbr Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv Genetic Background: involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Myf5^tm2Tajb/Myf5^tm2Tajb Genetic Background: involves: 129S2/SvPas * C3H/HeHa * C57BL * M. m. castaneus * M. m musculus Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Ctss^tm1Hap/Ctss^tm1Hap,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S2/SvPas * C57BL/10ScSn Allelic Composition: Dmd^tm1Kmf/Y Genetic Background: involves: C57BL/6
MP:0009415	skeletal muscle degeneration	"pathological deterioration of skeletal muscle tissue, often accompanied by loss of function" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Creb1^tm1.1Berd/Creb1^tm1.1Berd,Dmd^mdx/Y Genetic Background: B.Cg-Creb1^tm1.1Berd Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0009416	cardiac muscle degeneration	"pathological deterioration of cardiac muscle tissue, often accompanied by loss of function" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0009417	skeletal muscle atrophy	"a wasting of skeletal muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0009419	skeletal muscle fibrosis	"formation of fibrous tissue within skeletal muscle as a result of repair or a reactive process" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Dmd^mdx,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-2Cv/Dmd^mdx-2Cv Genetic Background: B6Ros.Cg-Dmd^mdx-2Cv Allelic Composition: Dmd^mdx-2Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-2Cv Allelic Composition: Dmd^mdx-3Cv/Dmd^mdx-3Cv Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv Allelic Composition: Dmd^mdx-4Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-4Cv Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv Allelic Composition: Cmah^tm1Avrk/Cmah^tm1Avrk,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Dmd^mdx,Mamstr^tm1.2Eno/Mamstr^tm1.2Eno Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx Allelic Composition: Ctss^tm1Hap/Ctss^tm1Hap,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S2/SvPas * C57BL/10ScSn
MP:0009420	skeletal muscle endomysial fibrosis	"replacement of the layer of connective tissue that ensheaths a muscle fiber by fibrous tissue resulting in separation of individual fibers" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Utrn^tm1Jrs/Utrn⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn
MP:0009461	skeletal muscle hypertrophy	"increase in the bulk size of the skeletal muscle due to cell enlargement" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn
MP:0010024	increased total body fat amount	"greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx
MP:0010053	decreased grip strength	"reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv Allelic Composition: Dmd^mdx/Dmd^mdx,Dusp1^tm1Brv/Dusp1^tm1Brv Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J Allelic Composition: Dmd^tm1Kmf/Y Genetic Background: involves: C57BL/6
MP:0010090	increased circulating creatine kinase level	"an elevation in the concentration in the blood of an enzyme that catalyzes the reversible transfer of creatine to phosphocreatine" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc⁺ Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dag1^tm1.1Swin/Dag1^tm1.1Swin,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/10ScSn Allelic Composition: Dag1^tm1.1Swin/Dag1^tm1.1Swin,Dmd^mdx/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J Allelic Composition: Ctss^tm1Hap/Ctss^tm1Hap,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S2/SvPas * C57BL/10ScSn Allelic Composition: Dmd^tm1Kmf/Y Genetic Background: involves: C57BL/6
MP:0010106	abnormal circulating pyruvate kinase level	"abnormal concentration in the blood of the phosphotransferase in the glycolytic pathway that catalyzes the transfer of phosphate from phosphoenolpyruvate to ADP, forming ATP and p; deficiency results in hemolytic anemia" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Dbh^tm2(Th)Rpa/Dbh⁺,Th^tm1Rpa/Th^tm1Rpa Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSnJ Allelic Composition: Dmd^mdx/Y,Nos1^tm1Plh/Nos1^tm1Plh Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd⁺,Nos1^tm1Plh/Nos1^tm1Plh Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd⁺ Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn
MP:0010226	increased quadriceps weight	"increase in the weight of the group of four muscles (rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis) which extend down the front of the thigh and are the major extensors of the knee joint" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0010227	decreased quadriceps weight	"reduction in the weight of the group of four muscles (rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis) which extend down the front of the thigh and are the major extensors of the knee joint" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx
MP:0010238	increased skeletal muscle weight	"greater than average skeletal muscle weight" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0010239	decreased skeletal muscle weight	"less than average skeletal muscle weight" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx,Dusp1^tm1Brv/Dusp1^tm1Brv Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Mamstr^tm1.2Eno/Mamstr^tm1.2Eno Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx
MP:0010252	anterior subcapsular cataracts	"a lens opacity localized beneath the anterior lens capsule" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn
MP:0010254	nuclear cataracts	"a lens opacity located in the dense, central part of the lens" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn
MP:0010392	prolonged QRS complex duration	"increase in the length of time of the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarize prior to their contraction; prolongation of the QRS complex duration reflects slowed conduction in the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv/J Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0010509	decreased P wave amplitude	"reduction in the size (height or maximum displacement) of the P wave" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv/J
MP:0010579	increased heart left ventricle size	"greater than average size of the left ventricle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0010581	abnormal atrium myocardial trabeculae morphology	"any structural anomaly of the supporting bundles of muscular fibers lining the walls of the atria" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx
MP:0010632	cardiac muscle necrosis	"pathological death of cardiomyocytes or a portion of the cardiac muscle tissue; usually due to irreversible damage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cmah^tm1Avrk/Cmah^tm1Avrk,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129X1/SvJ * C57BL/10ScSn
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Dmd^mdx/Y,Dtna^tm1Jrs/Dtna^tm1Jrs,Utrn^tm1Jrs/Utrn^tm1Jrs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn Allelic Composition: Dmd^mdx/Dmd^mdx,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Foxk1^tm1Djg/Foxk1^tm1Djg Genetic Background: involves: 129S4/SvJae * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Y Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn Allelic Composition: Barx2^tm1Rsd/Barx2^tm1Rsd,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn
MP:0011110	partial preweaning lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Dmd^mdx-3Cv/Dmd^mdx-3Cv Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv Allelic Composition: Dmd^mdx-3Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-3Cv
MP:0011628	increased mitochondria number	"greater than normal number of the cellular organelles responsible for energy production" [MGI:csmith]	Show Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0011631	decreased mitochondria size	"reduced size of the cellular organelles responsible for energy production" [MGI:csmith]	Show Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0011633	abnormal mitochondrial shape	"any anomaly in the characteristic surface outline or contour of a mitochondria" [MGI:csmith]	Show Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0011636	disorganized mitochondrial cristae	"derangement of the pattern of the inward folds of the mitochondrial inner membrane" [MGI:csmith]	Show Allelic Composition: Dmd^mdx-4Cv/Dmd^mdx-4Cv,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: B6.Cg-Terc^tm1Rdp Dmd^mdx-4Cv
MP:0011925	abnormal heart echocardiography feature	"any anomaly in echocardiographic representation of systolic and diastolic function, ventricular compliance, valvular function, or interventricular septum features" [MPD:Molly]	Show Allelic Composition: Dmd^tm1.1Know/Dmd^tm1.1Know,Tg(Myh6-2A)#Know/0,A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/0 Genetic Background:* involves: BALB/c * C3H * C57BL/6 * FVB/N
MP:0011952	decreased cardiac stroke volume	"reduction in the volume of blood pushed into the aorta with each beat of the heart" [MGI:csmith]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0011966	abnormal auditory brainstem response waveform shape	"any anomaly in the characteristic pattern of electrical activity recording of a series of vertex positive waves generated by neurons in the ascending auditory system, that can be recorded from scalp electrograms by using computer-averaged responses to short tone bursts" [MGI:csmith]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0011967	increased or absent threshold for auditory brainstem response	"increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J
MP:0012106	impaired exercise endurance	"impaired performance during controlled physical activity" [MGI:smb]	Show Allelic Composition: Dmd^mdx/Y,Terc^tm1Rdp/Terc^tm1Rdp Genetic Background: involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL Allelic Composition: Dmd^mdx/Dmd^mdx,Prkdc^scid/Prkdc^scid Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn * CB17 Allelic Composition: Ctss^tm1Hap/Ctss^tm1Hap,Dmd^mdx/Dmd^mdx Genetic Background: involves: 129S2/SvPas * C57BL/10ScSn
MP:0013237	abnormal skeletal muscle regeneration	"anomaly in the ability to repair skeletal muscle after injury or disease" [MGI:csmith]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Dmd^mdx,Mmp9^tm1Tvu/Mmp9^tm1Tvu Genetic Background: B10.Cg-Mmp9^tm1Tvu Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx,Mmp9^tm1Tvu/Mmp9⁺ Genetic Background: B10.Cg-Mmp9^tm1Tvu Dmd^mdx Allelic Composition: Creb1^tm1.1Berd/Creb1^tm1.1Berd,Dmd^mdx/Y Genetic Background: B.Cg-Creb1^tm1.1Berd Dmd^mdx Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J
MP:0013467	diaphragmitis	"inflammation of the diaphragm" [MGI:Anna]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: involves: C57BL/10ScSn Allelic Composition: Dmd^mdx/Y,Utrn^tm1Jrs/Utrn⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn
MP:0014143	decreased body fat mass	"decreased physical bulk or volume of fat in the whole body" [MGI:csmith]	Show Allelic Composition: Dmd^mdx/Y Genetic Background: C57BL/10ScSn-Dmd^mdx Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv
MP:0020309	increased creatine kinase activity	"increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+)." [GOC:NV, PMID:18977227]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: C57BL/10ScSn-Dmd^mdx/J Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: D2.B10-Dmd^mdx/J Allelic Composition: Dmd^mdx/Y,Mirc37^tm1Boet/Mirc37^tm1Boet Genetic Background: involves: C57BL/10ScSn
MP:0020330	increased capillary density	"increase in the number of capillaries in a given cross-sectional area of a tissue" [ORCID: orcid.org/0000-0003-4606-0597, PMID:20705734]	Show Allelic Composition: Dmd^mdx-5Cv/Dmd^mdx-5Cv,Flt1^tm1Jrt/Flt1⁺ Genetic Background: involves: C3HA * C57BL/6Ros
MP:0030428	abnormal scalene muscle morphology	"any structural anomaly of any of the three pairs of muscles in the lateral neck, namely the scalenus anterior, scalenus medius, and scalenus posterior; the scalenes are innervated by the cervical spinal nerves C4-C8, act as accessory muscles of respiration, and perform flexion at the neck" [http://teachmeanatomy.info/neck/muscles/scalene/, https://en.wikipedia.org/wiki/Scalene_muscles]	Show Allelic Composition: Dmd^mdx/Dmd^mdx Genetic Background: involves: C57BL/10ScSn

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