ENSGALG00000020523


Gallus gallus

Features
Gene ID: ENSGALG00000020523
  
Biological name :TOPORS
  
Synonyms : TOP1 binding arginine/serine rich protein / TOPORS
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase Topors / Q80Z37 / Q9NS56
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 67114959
Gene end: 67119131
  
Corresponding Affymetrix probe sets: GgaAffx.10043.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000032131
NCBI entrez gene - 427342     See in Manteia.
RefSeq - XM_004949524
RefSeq - XM_004949525
swissprot - F1NAF2
Ensembl - ENSGALG00000020523
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 toporsaENSDARG00000037260Danio rerio
 Q9NS56ENSG00000197579Homo sapiens
 Q80Z37ENSMUSG00000036822Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006513 protein monoubiquitination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:0016925 protein sumoylation IEA
 biological_processGO:0034504 protein localization to nucleus IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0051443 positive regulation of ubiquitin-protein transferase activity IEA
 biological_processGO:0051457 maintenance of protein location in nucleus IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0000930 gamma-tubulin complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0032391 photoreceptor connecting cilium IEA
 cellular_componentGO:0036064 ciliary basal body IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003823 antigen binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0019789 SUMO transferase activity IEA
 molecular_functionGO:0044547 DNA topoisomerase binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors
SUMOylation of SUMOylation proteins
SUMOylation of immune response proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008435 SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*  / reaction / complex
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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