ENSGALG00000021031


Gallus gallus

Features
Gene ID: ENSGALG00000021031
  
Biological name :ACKR3
  
Synonyms : ACKR3 / atypical chemokine receptor 3
  
Possible biological names infered from orthology : P25106 / P56485
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 5036416
Gene end: 5041363
  
Corresponding Affymetrix probe sets: Gga.13980.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042614
Ensembl peptide - ENSGALP00000049435
Ensembl peptide - ENSGALP00000057326
NCBI entrez gene - 428997     See in Manteia.
RefSeq - XM_015289178
RefSeq - NM_001083362
RefSeq Peptide - NP_001076831
swissprot - R4GKC2
Ensembl - ENSGALG00000021031
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ackr3aENSDARG00000062478Danio rerio
 ackr3bENSDARG00000058179Danio rerio
 ACKR3ENSG00000144476Homo sapiens
 Ackr3ENSMUSG00000044337Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR182 / G protein-coupled receptor 182 / O15218*ENSGALG0000004217731
AGTR2 / angiotensin II receptor type 2 / P35374* / P50052* / Type-2 angiotensin II receptor *ENSGALG0000000593627
RXFP3 / relaxin/insulin like family peptide receptor 3 / Q8BGE9* / Q9NSD7* / Relaxin-3 receptor 1 *ENSGALG0000001741126
AGTR1 / P79785 / Type-1 angiotensin II receptor / P30556* / P29755* / Agtr1a* / Agtr1b* / P29754* / angiotensin II receptor type 1* / Type-1A angiotensin II receptor * / Type-1B angiotensi...ENSGALG0000003851225
APLNR / apelin receptor / P35414* / Q9WV08*ENSGALG0000000484124
BDKRB1 / bradykinin receptor B1 / P46663* / Q61125* / B1 bradykinin receptor *ENSGALG0000002038622
BDKRB2 / bradykinin receptor B2 / P30411* / P32299* / B2 bradykinin receptor *ENSGALG0000001108021
GPR15* / P49685* / Q0VDU3* / G protein-coupled receptor 15*ENSGALG0000001513321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001416  Atypical chemokine receptor 3
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0015026 coreceptor activity IEA
 molecular_functionGO:0016494 C-X-C chemokine receptor activity IEA
 molecular_functionGO:0019956 chemokine binding IEA
 molecular_functionGO:0019958 C-X-C chemokine binding IEA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000041346 CXCL12 / C-X-C motif chemokine ligand 12 / P40224* / P48061* / Stromal cell-derived factor 1 *  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr