Manteia

ENSDARG00000058179

Danio rerio

Features

Gene ID:	ENSDARG00000058179

Biological name :	ackr3b

Synonyms :	ackr3b / atypical chemokine receptor 3b

Possible biological names infered from orthology :	ACKR3 / atypical chemokine receptor 3 / P25106 / P56485

Species:	Danio rerio

Chr. number:	6
Strand:	-1
Band:
Gene start:	15751982
Gene end:	15757867

Corresponding Affymetrix probe sets:	Dr.18178.1.S1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000063664 NCBI entrez gene - 561050 See in Manteia. RefSeq - NM_001083832 RefSeq Peptide - NP_001077301 swissprot - A4IG54 ZFIN ID - ZDB-GENE-031116-61 Ensembl - ENSDARG00000058179

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
ACKR3	ENSGALG00000021031	Gallus gallus
ACKR3	ENSG00000144476	Homo sapiens
Ackr3	ENSMUSG00000044337	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
ackr3a / atypical chemokine receptor 3a / ACKR3* / P25106* / P56485* / atypical chemokine receptor 3*	ENSDARG00000062478	59
gpr182 / G protein-coupled receptor 182 / O15218*	ENSDARG00000036616	30
Q7SZP9 / aplnra / apelin receptor a / APLNR* / Q9WV08* / P35414* / apelin receptor*	ENSDARG00000002172	27
A0T2N3 / aplnrb / apelin receptor b / APLNR* / Q9WV08* / P35414* / apelin receptor*	ENSDARG00000036670	27
agtr1b / angiotensin II receptor, type 1b / AGTR1* / P29755* / Agtr1a* / P29754* / P30556* / angiotensin II receptor type 1* / Type-1B angiotensin II receptor * / Type-1A angiotensin II receptor *	ENSDARG00000045443	25
agtr2 / angiotensin II receptor, type 2 / P35374* / P50052* / Type-2 angiotensin II receptor *	ENSDARG00000035552	25
rxfp3.2b / relaxin/insulin-like family peptide receptor 3.2b	ENSDARG00000061846	25
rxfp3 / relaxin/insulin-like family peptide receptor 3 / Q8BGE9* / Q9NSD7* / Relaxin-3 receptor 1 *	ENSDARG00000057410	25
gpr25 / G protein-coupled receptor 25 / O00155* / P0C5I1* / Probable G-protein coupled receptor 25 *	ENSDARG00000057112	24
agtr1a / angiotensin II receptor, type 1a / AGTR1* / P29755* / Agtr1b* / P29754* / P30556* / angiotensin II receptor type 1* / Type-1B angiotensin II receptor * / Type-1A angiotensin II receptor *	ENSDARG00000018616	23
rxfp3.3b / relaxin/insulin-like family peptide receptor 3.3b / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000059348	23
aplnr2 / apelin receptor 2	ENSDARG00000004447	23
rxfp3.3a3 / relaxin/insulin-like family peptide receptor 3.3a3 / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000069246	23
rxfp3.3a1 / relaxin/insulin-like family peptide receptor 3.3a1 / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000069028	22
rxfp3.3a2 / relaxin/insulin-like family peptide receptor 3.3a2 / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000062111	22
si:dkey-63b1.1 / BDKRB2* / P30411* / P32299* / bradykinin receptor B2* / B2 bradykinin receptor *	ENSDARG00000043664	21
bdkrb1 / bradykinin receptor B1 / P46663* / Q61125* / B1 bradykinin receptor *	ENSDARG00000020744	20

Protein motifs (from Interpro)

Interpro ID	Name
IPR000276	G protein-coupled receptor, rhodopsin-like
IPR001416	Atypical chemokine receptor 3

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001525	angiogenesis	IEA
biological_process	GO:0001570	vasculogenesis	IEA
biological_process	GO:0001764	neuron migration	IMP
biological_process	GO:0006935	chemotaxis	IMP
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0008354	germ cell migration	IMP
biological_process	GO:0021730	trigeminal sensory nucleus development	IMP
biological_process	GO:0048920	posterior lateral line neuromast primordium migration	IMP
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IEA
molecular_function	GO:0015026	coreceptor activity	IEA
molecular_function	GO:0019956	chemokine binding	IMP

Pathways (from Reactome)

Pathway description

Chemokine receptors bind chemokines

G alpha (i) signalling events

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000054	pericardium	pericardium increased size , abnormal	Show
ZFA:0000243	neuromast	neuromast decreased amount , abnormal	Show
ZFA:0000940	posterior lateral line neuromast	posterior lateral line neuromast decreased amount , abnormal	Show
ZFA:0001157	posterior lateral line primordium	posterior lateral line primordium shape , abnormal posterior lateral line primordium split , abnormal posterior lateral line primordium cell increased length , abnormal	Show
ZFA:0001285	intersegmental vessel	intersegmental vessel morphology , abnormal	Show
ZFA:0001286	caudal vein plexus	caudal vein plexus malformed , abnormal	Show
ZFA:0005768	trigeminal sensory neuron	trigeminal sensory neuron mislocalised , abnormal trigeminal sensory neuron cell migration process quality , abnormal	Show
ZFA:0009288	primordial germ cell	primordial germ cell mislocalised , abnormal primordial germ cell cellular motility , abnormal primordial germ cell positional polarity , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000037116	cxcl12a / chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) / CXCL12* / P40224* / P48061* / Stromal cell-derived factor 1 * / C-X-C motif chemokine ligand 12*	/ reaction / complex
ENSDARG00000055100	cxcl12b / chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) / CXCL12* / P40224* / P48061* / Stromal cell-derived factor 1 * / C-X-C motif chemokine ligand 12*	/ reaction / complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr