Manteia

ENSDARG00000036670

Danio rerio

Features

Gene ID:	ENSDARG00000036670

Biological name :	aplnrb

Synonyms :	A0T2N3 / apelin receptor b / aplnrb

Possible biological names infered from orthology :	apelin receptor / APLNR / P35414 / Q9WV08

Species:	Danio rerio

Chr. number:	10
Strand:	1
Band:
Gene start:	8629275
Gene end:	8631361

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000108783 NCBI entrez gene - 565492 See in Manteia. RefSeq - NM_001030197 RefSeq Peptide - NP_001025368 swissprot - A0T2N3 ZFIN ID - ZDB-GENE-050913-90 Ensembl - ENSDARG00000036670

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
APLNR	ENSGALG00000004841	Gallus gallus
APLNR	ENSG00000134817	Homo sapiens
Aplnr	ENSMUSG00000044338	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q7SZP9 / aplnra / apelin receptor a / APLNR* / Q9WV08* / P35414* / apelin receptor*	ENSDARG00000002172	78
aplnr2 / apelin receptor 2	ENSDARG00000004447	45
agtr1b / angiotensin II receptor, type 1b / AGTR1* / P29755* / Agtr1a* / P29754* / P30556* / angiotensin II receptor type 1* / Type-1B angiotensin II receptor * / Type-1A angiotensin II receptor *	ENSDARG00000045443	32
agtr1a / angiotensin II receptor, type 1a / AGTR1* / P29755* / Agtr1b* / P29754* / P30556* / angiotensin II receptor type 1* / Type-1B angiotensin II receptor * / Type-1A angiotensin II receptor *	ENSDARG00000018616	31
agtr2 / angiotensin II receptor, type 2 / P35374* / P50052* / Type-2 angiotensin II receptor *	ENSDARG00000035552	30
rxfp3.2b / relaxin/insulin-like family peptide receptor 3.2b	ENSDARG00000061846	30
gpr25 / G protein-coupled receptor 25 / O00155* / P0C5I1* / Probable G-protein coupled receptor 25 *	ENSDARG00000057112	29
ackr3a / atypical chemokine receptor 3a / ACKR3* / P25106* / P56485* / atypical chemokine receptor 3*	ENSDARG00000062478	28
rxfp3.3b / relaxin/insulin-like family peptide receptor 3.3b / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000059348	28
rxfp3.3a1 / relaxin/insulin-like family peptide receptor 3.3a1 / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000069028	27
ackr3b / atypical chemokine receptor 3b / ACKR3* / P25106* / P56485* / atypical chemokine receptor 3*	ENSDARG00000058179	27
rxfp3 / relaxin/insulin-like family peptide receptor 3 / Q8BGE9* / Q9NSD7* / Relaxin-3 receptor 1 *	ENSDARG00000057410	27
rxfp3.3a3 / relaxin/insulin-like family peptide receptor 3.3a3 / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000069246	27
rxfp3.3a2 / relaxin/insulin-like family peptide receptor 3.3a2 / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000062111	27
si:dkey-63b1.1 / BDKRB2* / P30411* / P32299* / bradykinin receptor B2* / B2 bradykinin receptor *	ENSDARG00000043664	27
bdkrb1 / bradykinin receptor B1 / P46663* / Q61125* / B1 bradykinin receptor *	ENSDARG00000020744	23
gpr182 / G protein-coupled receptor 182 / O15218*	ENSDARG00000036616	21

Protein motifs (from Interpro)

Interpro ID	Name
IPR000248	Angiotensin II receptor family
IPR000276	G protein-coupled receptor, rhodopsin-like
IPR017452	GPCR, rhodopsin-like, 7TM

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001525	angiogenesis	IEA
biological_process	GO:0001570	vasculogenesis	ISS
biological_process	GO:0001702	gastrulation with mouth forming second	IMP
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007275	multicellular organism development	IEA
biological_process	GO:0007369	gastrulation	IEA
biological_process	GO:0007507	heart development	IMP
biological_process	GO:0008078	mesodermal cell migration	IMP
biological_process	GO:0016477	cell migration	IMP
biological_process	GO:0035479	angioblast cell migration from lateral mesoderm to midline	IMP
biological_process	GO:0035987	endodermal cell differentiation	IGI
biological_process	GO:0043951	negative regulation of cAMP-mediated signaling	ISS
biological_process	GO:0045766	positive regulation of angiogenesis	ISS
biological_process	GO:0048738	cardiac muscle tissue development	IMP
biological_process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	ISS
biological_process	GO:0060183	apelin receptor signaling pathway	IEA
biological_process	GO:0060976	coronary vasculature development	ISS
biological_process	GO:0090162	establishment of epithelial cell polarity	IMP
biological_process	GO:1900107	regulation of nodal signaling pathway	IGI
biological_process	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	ISS
biological_process	GO:1904325	positive regulation of inhibitory G-protein coupled receptor phosphorylation	ISS
cellular_component	GO:0005886	plasma membrane	ISS
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IEA
molecular_function	GO:0060182	apelin receptor activity	IDA

Pathways (from Reactome)

Pathway description

G alpha (i) signalling events

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000008	brain	brain necrotic , abnormal	Show
ZFA:0000028	heart primordium	heart primordium hypoplastic , abnormal heart primordium decreased distribution , abnormal heart primordium decreased amount , abnormal	Show
ZFA:0000054	pericardium	pericardium edematous , abnormal	Show
ZFA:0000114	heart	heart aplastic , abnormal heart decreased size , abnormal heart hypoplastic , abnormal	Show
ZFA:0009065	endothelial cell	endothelial cell decreased amount , abnormal	Show
ZFA:0009139	endodermal cell	endodermal cell decreased distribution , abnormal endodermal cell decreased amount , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr