ENSGALG00000021601


Gallus gallus

Features
Gene ID: ENSGALG00000021601
  
Biological name :EPS15L1
  
Synonyms : epidermal growth factor receptor pathway substrate 15 like 1 / EPS15L1
  
Possible biological names infered from orthology : Epidermal growth factor receptor substrate 15-like 1 / Q60902 / Q9UBC2
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 4356516
Gene end: 4388732
  
Corresponding Affymetrix probe sets: Gga.18726.1.S1_s_at (Chicken Array)   GgaAffx.26055.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050700
Ensembl peptide - ENSGALP00000006220
NCBI entrez gene - 420147     See in Manteia.
RefSeq - XM_015300173
RefSeq - XM_015300171
RefSeq - XM_015300172
RefSeq - XM_015300169
RefSeq - XM_015300170
swissprot - F1P2G2
swissprot - A0A1D5PD59
Ensembl - ENSGALG00000021601
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01066725.1ENSDARG00000100700Danio rerio
 eps15l1aENSDARG00000042670Danio rerio
 Q9UBC2ENSG00000127527Homo sapiens
 Q60902ENSMUSG00000006276Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPS15 / epidermal growth factor receptor substrate 15 / P42566* / P42567* / epidermal growth factor receptor pathway substrate 15*ENSGALG0000001054348
ITSN2 / intersectin 2 / Q9NZM3*ENSGALG0000001650420
ITSN1 / intersectin 1 / Q15811* / Q9Z0R4*ENSGALG0000003667720
REPS1 / ralBP1-associated Eps domain-containing protein 1 / O54916* / Q96D71* / RALBP1 associated Eps domain containing 1*ENSGALG0000001382915
REPS2 / ralBP1-associated Eps domain-containing protein 2 / Q8NFH8* / RALBP1 associated Eps domain containing 2*ENSGALG0000001654512
EHD4 / EH domain containing 4 / Q9EQP2* / Q9H223* / EH domain-containing protein 4 *ENSGALG000000089509
EHD3 / EH domain-containing protein 3 / Q9NZN3* / Q9QXY6* / EH domain containing 3*ENSGALG000000090869
SRL / sarcalumenin precursor / Q7TQ48* / Q86TD4* / sarcalumenin*ENSGALG000000388845


Protein motifs (from Interpro)
Interpro ID Name
 IPR000261  EH domain
 IPR002048  EF-hand domain
 IPR003903  Ubiquitin interacting motif
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0030132 clathrin coat of coated pit IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
EGFR downregulation
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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