ENSMUSG00000006276


Mus musculus

Features
Gene ID: ENSMUSG00000006276
  
Biological name :Eps15l1
  
Synonyms : Epidermal growth factor receptor substrate 15-like 1 / Eps15l1 / Q60902
  
Possible biological names infered from orthology : epidermal growth factor receptor pathway substrate 15 like 1 / Q9UBC2
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B3.3
Gene start: 72340999
Gene end: 72421460
  
Corresponding Affymetrix probe sets: 10579663 (MoGene1.0st)   1424765_at (Mouse Genome 430 2.0 Array)   1446683_at (Mouse Genome 430 2.0 Array)   1447848_at (Mouse Genome 430 2.0 Array)   1449355_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000129739
Ensembl peptide - ENSMUSP00000148468
Ensembl peptide - ENSMUSP00000148484
NCBI entrez gene - 13859     See in Manteia.
MGI - MGI:104582
RefSeq - XM_017312560
RefSeq - NM_001122832
RefSeq - NM_001289859
RefSeq - NM_007944
RefSeq - XM_006509545
RefSeq - XM_006509546
RefSeq - XM_006509547
RefSeq - XM_006509548
RefSeq - XM_017312559
RefSeq - XM_006509544
RefSeq Peptide - NP_001116304
RefSeq Peptide - NP_001276788
RefSeq Peptide - NP_031970
swissprot - Q60902
swissprot - A0A1D5RLS1
Ensembl - ENSMUSG00000006276
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01066725.1ENSDARG00000100700Danio rerio
 eps15l1aENSDARG00000042670Danio rerio
 EPS15L1ENSGALG00000021601Gallus gallus
 Q9UBC2ENSG00000127527Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Eps15 / P42567 / Epidermal growth factor receptor substrate 15 / P42566* / epidermal growth factor receptor pathway substrate 15*ENSMUSG0000002855247
Itsn1 / Q9Z0R4 / Intersectin-1 / Q15811*ENSMUSG0000002295722
Itsn2 / intersectin 2 / Q9NZM3*ENSMUSG0000002064022
Reps1 / O54916 / RalBP1-associated Eps domain-containing protein 1 / Q96D71* / RALBP1 associated Eps domain containing 1*ENSMUSG0000001985415
Reps2 / RALBP1 associated Eps domain containing protein 2 / Q8NFH8* / RALBP1 associated Eps domain containing 2*ENSMUSG0000004085514
Ehd2 / Q8BH64 / EH domain-containing protein 2 / Q9NZN4* / EH domain containing 2*ENSMUSG0000007436410
Ehd3 / Q9QXY6 / EH domain-containing protein 3 / Q9NZN3* / EH domain containing 3*ENSMUSG0000002406510
Ehd4 / Q9EQP2 / EH domain-containing protein 4 / Q9H223* / EH domain containing 4*ENSMUSG000000272939
Ehd1 / Q9WVK4 / EH domain-containing protein 1 / Q9H4M9* / EH domain containing 1*ENSMUSG000000247729
Srl / Q7TQ48 / Sarcalumenin / Q86TD4*ENSMUSG000000225197


Protein motifs (from Interpro)
Interpro ID Name
 IPR000261  EH domain
 IPR002048  EF-hand domain
 IPR003903  Ubiquitin interacting motif
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030132 clathrin coat of coated pit IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0045296 cadherin binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
EGFR downregulation
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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