ENSGALG00000016504


Gallus gallus

Features
Gene ID: ENSGALG00000016504
  
Biological name :ITSN2
  
Synonyms : intersectin 2 / ITSN2
  
Possible biological names infered from orthology : Q9NZM3
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 104694953
Gene end: 104737279
  
Corresponding Affymetrix probe sets: Gga.7823.1.S1_at (Chicken Array)   GgaAffx.10556.1.S1_s_at (Chicken Array)   GgaAffx.12617.1.S1_at (Chicken Array)   GgaAffx.24985.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000026573
NCBI entrez gene - 421979     See in Manteia.
RefSeq - XM_015285036
RefSeq - XM_015285037
RefSeq - XM_015285038
RefSeq - XM_015285039
RefSeq - XM_015285040
RefSeq - XM_419989
RefSeq - XM_015285035
swissprot - E1BVT9
Ensembl - ENSGALG00000016504
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itsn2aENSDARG00000000161Danio rerio
 itsn2bENSDARG00000054973Danio rerio
 ITSN2ENSG00000198399Homo sapiens
 Itsn2ENSMUSG00000020640Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITSN1 / intersectin 1 / Q15811* / Q9Z0R4*ENSGALG0000003667761
EPS15 / epidermal growth factor receptor substrate 15 / P42566* / P42567* / epidermal growth factor receptor pathway substrate 15*ENSGALG0000001054312
EPS15L1 / epidermal growth factor receptor pathway substrate 15 like 1 / Q60902* / Q9UBC2* / Epidermal growth factor receptor substrate 15-like 1 *ENSGALG0000002160112
REPS1 / ralBP1-associated Eps domain-containing protein 1 / O54916* / Q96D71* / RALBP1 associated Eps domain containing 1*ENSGALG000000138297
EHD3 / EH domain-containing protein 3 / Q9NZN3* / Q9QXY6* / EH domain containing 3*ENSGALG000000090866
REPS2 / ralBP1-associated Eps domain-containing protein 2 / Q8NFH8* / RALBP1 associated Eps domain containing 2*ENSGALG000000165456
EHD4 / EH domain containing 4 / Q9EQP2* / Q9H223* / EH domain-containing protein 4 *ENSGALG000000089505
SRL / sarcalumenin precursor / Q7TQ48* / Q86TD4* / sarcalumenin*ENSGALG000000388843


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000219  Dbl homology (DH) domain
 IPR000261  EH domain
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR018247  EF-Hand 1, calcium-binding site
 IPR027029  Intersectin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:1903861 positive regulation of dendrite extension IEA
 cellular_componentGO:0005813 centrosome IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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