ENSGALG00000023338


Gallus gallus

Features
Gene ID: ENSGALG00000023338
  
Biological name :CBX2
  
Synonyms : CBX2 / chromobox 2
  
Possible biological names infered from orthology : Chromobox protein homolog 2 / P30658 / Q14781
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 9721862
Gene end: 9729512
  
Corresponding Affymetrix probe sets: Gga.13796.1.S1_at (Chicken Array)   GgaAffx.8751.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000037639
swissprot - E1BX64
Ensembl - ENSGALG00000023338
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbx2ENSDARG00000044938Danio rerio
 CBX2ENSG00000173894Homo sapiens
 Cbx2ENSMUSG00000025577Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CBX4 / E3 SUMO-protein ligase CBX4 / O00257* / O55187* / chromobox 4*ENSGALG0000003591114
CBX6 / chromobox 6 / O95503* / Q9DBY5* / Chromobox protein homolog 6 *ENSGALG0000003686712
CBX8 / chromobox 8 / Q9HC52* / Q9QXV1* / Chromobox protein homolog 8 *ENSGALG0000002654810
CBX7 / chromobox 7 / O95931* / Q8VDS3* / Chromobox protein homolog 7 *ENSGALG000000412368


Protein motifs (from Interpro)
Interpro ID Name
 IPR033773  CBX family C-terminal motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045137 development of primary sexual characteristics IEA
 cellular_componentGO:0000791 euchromatin IEA
 cellular_componentGO:0000792 heterochromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0031519 PcG protein complex IEA
 cellular_componentGO:0035102 PRC1 complex IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0035064 methylated histone binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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