ENSGALG00000035911


Gallus gallus

Features
Gene ID: ENSGALG00000035911
  
Biological name :CBX4
  
Synonyms : CBX4 / E3 SUMO-protein ligase CBX4
  
Possible biological names infered from orthology : chromobox 4 / O00257 / O55187
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 9694212
Gene end: 9698056
  
Corresponding Affymetrix probe sets: Gga.49.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058306
NCBI entrez gene - 395354     See in Manteia.
RefSeq - NM_204642
RefSeq Peptide - NP_989973
swissprot - A0A1D5PZ96
Ensembl - ENSGALG00000035911
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbx4ENSDARG00000099441Danio rerio
 CBX4ENSG00000141582Homo sapiens
 Cbx4ENSMUSG00000039989Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CBX2 / chromobox 2 / P30658* / Q14781* / Chromobox protein homolog 2 *ENSGALG0000002333817
CBX6 / chromobox 6 / O95503* / Q9DBY5* / Chromobox protein homolog 6 *ENSGALG0000003686716
CBX8 / chromobox 8 / Q9HC52* / Q9QXV1* / Chromobox protein homolog 8 *ENSGALG0000002654814
CBX7 / chromobox 7 / O95931* / Q8VDS3* / Chromobox protein homolog 7 *ENSGALG0000004123613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR016197  Chromo-like domain superfamily
 IPR017984  Chromo domain subgroup
 IPR023779  Chromo domain, conserved site
 IPR023780  Chromo domain
 IPR033773  CBX family C-terminal motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0016925 protein sumoylation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0031519 PcG protein complex IEA
 cellular_componentGO:0035102 PRC1 complex IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003727 single-stranded RNA binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0032183 SUMO binding IEA
 molecular_functionGO:0035064 methylated histone binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0051219 phosphoprotein binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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