ENSGALG00000025898


Gallus gallus

Features
Gene ID: ENSGALG00000025898
  
Biological name :SMAD6
  
Synonyms : mothers against decapentaplegic homolog 6 / SMAD6
  
Possible biological names infered from orthology : O35182 / O43541 / SMAD family member 6
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 18699479
Gene end: 18727091
  
Corresponding Affymetrix probe sets: Gga.3878.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041470
Ensembl peptide - ENSGALP00000053011
Ensembl peptide - ENSGALP00000049933
NCBI entrez gene - 374096     See in Manteia.
RefSeq - NM_204248
RefSeq Peptide - NP_989579
swissprot - A0A1D5PJL5
swissprot - A0A1D5PB14
swissprot - R4GHC9
Ensembl - ENSGALG00000025898
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smad6bENSDARG00000031763Danio rerio
 SMAD6ENSG00000137834Homo sapiens
 Smad6ENSMUSG00000036867Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SMAD7B / Gallus gallus TGF-beta signal pathway antagonist Smad7 (SMAD7B), mRNA. / SMAD7* / O35253* / O15105* / SMAD family member 7*ENSGALG0000002954549
SMAD7* / O15105* / O35253* / SMAD family member 7*ENSGALG0000003716047
SMAD2* / Q15796* / Q62432* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *ENSGALG0000001418427
SMAD5 / Q56I99 / Mothers against decapentaplegic homolog 5 / P97454* / Q99717* / SMAD family member 5*ENSGALG0000000630927
SMAD2Z / SMAD2* / Q62432* / Q15796* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *ENSGALG0000003600127
SMAD9 / mothers against decapentaplegic homolog 9 / O15198* / Q9JIW5* / SMAD family member 9*ENSGALG0000001705027
SMAD1 / mothers against decapentaplegic homolog 1 / P70340* / Q15797* / SMAD family member 1*ENSGALG0000000997726
SMAD4* / P97471* / Q13485* / SMAD family member 4* / Mothers against decapentaplegic homolog 4 *ENSGALG0000003941726
SMAD3 / mothers against decapentaplegic homolog 3 / P84022* / Q8BUN5* / SMAD family member 3*ENSGALG0000003570124


Protein motifs (from Interpro)
Interpro ID Name
 IPR001132  SMAD domain, Dwarfin-type
 IPR003619  MAD homology 1, Dwarfin-type
 IPR008984  SMAD/FHA domain superfamily
 IPR013019  MAD homology, MH1
 IPR013790  Dwarfin
 IPR017855  SMAD-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0010693 negative regulation of alkaline phosphatase activity IMP
 biological_processGO:0032331 negative regulation of chondrocyte differentiation IMP
 biological_processGO:0050767 regulation of neurogenesis IMP
 biological_processGO:1902832 negative regulation of cell proliferation in dorsal spinal cord IMP
 biological_processGO:1902844 positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway IMP
 biological_processGO:1902879 negative regulation of BMP signaling pathway involved in spinal cord association neuron specification IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
Signaling by BMP


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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