ENSGALG00000026137


Gallus gallus

Features
Gene ID: ENSGALG00000026137
  
Biological name :CDKN2B
  
Synonyms : CDKN2B
  
Possible biological names infered from orthology : CDKN2A / Cyclin-dependent kinase 4 inhibitor B / cyclin dependent kinase inhibitor 2A / cyclin dependent kinase inhibitor 2B / P42771 / P42772 / P55271 / Q8N726
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 78638971
Gene end: 78642380
  
Corresponding Affymetrix probe sets: Gga.5007.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042709
NCBI entrez gene - 395076     See in Manteia.
RefSeq - NM_204433
RefSeq Peptide - NP_989764
swissprot - Q7ZT27
Ensembl - ENSGALG00000026137
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdkn2a/bENSDARG00000037262Danio rerio
 CDKN2AENSG00000147889Homo sapiens
 CDKN2BENSG00000147883Homo sapiens
 Cdkn2bENSMUSG00000073802Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDKN2C / cyclin dependent kinase inhibitor 2C / P42773* / Q60772* / Cyclin-dependent kinase 4 inhibitor C *ENSGALG0000001053742


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0048536 spleen development IEA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
Oncogene Induced Senescence
SUMOylation of DNA damage response and repair proteins
Cyclin D associated events in G1
Regulation of RUNX3 expression and activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000009476 CDK6 / cyclin dependent kinase 6 / Q00534* / Q64261*  / complex / reaction
 ENSGALG00000009942 MDM2 / MDM2 proto-oncogene / P23804* / Q00987* / E3 ubiquitin-protein ligase Mdm2 *  / complex






 

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contact: otassy@igbmc.fr