ENSGALG00000026757


Gallus gallus

Features
Gene ID: ENSGALG00000026757
  
Biological name :DHFR
  
Synonyms : DHFR
  
Possible biological names infered from orthology : DHFR2 / dihydrofolate reductase / dihydrofolate reductase 2 / P00374 / P00375 / Q86XF0
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 64052860
Gene end: 64068912
  
Corresponding Affymetrix probe sets: Gga.2883.1.S1_at (Chicken Array)   GgaAffx.11934.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041459
Ensembl peptide - ENSGALP00000050839
Ensembl peptide - ENSGALP00000048112
NCBI entrez gene - 427317     See in Manteia.
RefSeq - NM_001006584
RefSeq Peptide - NP_001006584
swissprot - A3RKL3
swissprot - A0A1D5PDJ4
swissprot - A0A1D5P5Y8
Ensembl - ENSGALG00000026757
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhfrENSDARG00000004251Danio rerio
 DHFRENSG00000228716Homo sapiens
 DHFR2ENSG00000178700Homo sapiens
 DhfrENSMUSG00000021707Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001796  Dihydrofolate reductase domain
 IPR012259  Dihydrofolate reductase
 IPR017925  Dihydrofolate reductase conserved site
 IPR024072  Dihydrofolate reductase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006729 tetrahydrobiopterin biosynthetic process IEA
 biological_processGO:0046654 tetrahydrofolate biosynthetic process IEA
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:2000121 regulation of removal of superoxide radicals IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0004146 dihydrofolate reductase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr