ENSGALG00000028530


Gallus gallus

Features
Gene ID: ENSGALG00000028530
  
Biological name :PRKACB
  
Synonyms : PRKACB / protein kinase cAMP-activated catalytic subunit beta
  
Possible biological names infered from orthology : P22694 / P68181 / protein kinase, cAMP dependent, catalytic, beta
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 16711494
Gene end: 16776511
  
Corresponding Affymetrix probe sets: Gga.18003.1.S1_at (Chicken Array)   Gga.18936.1.S1_at (Chicken Array)   GgaAffx.22700.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041979
Ensembl peptide - ENSGALP00000053824
Ensembl peptide - ENSGALP00000048315
Ensembl peptide - ENSGALP00000046173
Ensembl peptide - ENSGALP00000044534
NCBI entrez gene - 424542     See in Manteia.
RefSeq - XM_422379
RefSeq - XM_015290884
RefSeq - XM_015290886
RefSeq - XM_015290887
RefSeq - XM_015290888
RefSeq - XM_015290889
RefSeq - XM_004936658
RefSeq - XM_004936659
swissprot - A0A1D5P6I8
swissprot - A0A1D5P0J5
swissprot - A0A1D5NW04
swissprot - R4GIN8
swissprot - A0A1D5PLV3
Ensembl - ENSGALG00000028530
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prkacbbENSDARG00000059125Danio rerio
 P22694ENSG00000142875Homo sapiens
 P68181ENSMUSG00000005034Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRKX / protein kinase, X-linked / P51817* / Q922R0* / cAMP-dependent protein kinase catalytic subunit PRKX *ENSGALG0000004275942
PRKG1 / protein kinase, cGMP-dependent, type I / P0C605* / Q13976*ENSGALG0000000380540
PRKG2 / protein kinase, cGMP-dependent, type II / Q13237*ENSGALG0000001090938
ENSGALG0000004254333


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0070613 regulation of protein processing IEA
 biological_processGO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0045171 intercellular bridge IEA
 cellular_componentGO:0097546 ciliary base IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004691 cAMP-dependent protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA


Pathways (from Reactome)
Pathway description
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Rap1 signalling
Regulation of insulin secretion
Vasopressin regulates renal water homeostasis via Aquaporins
CREB phosphorylation through the activation of Adenylate Cyclase
GLI3 is processed to GLI3R by the proteasome
Hedgehog off state
CD209 (DC-SIGN) signaling
MAPK6/MAPK4 signaling
HDL assembly
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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