ENSGALG00000031343


Gallus gallus

Features
Gene ID: ENSGALG00000031343
  
Biological name :ECE1
  
Synonyms : ECE1 / endothelin converting enzyme 1
  
Possible biological names infered from orthology : P42892 / Q4PZA2
  
Species: Gallus gallus
  
Chr. number: 21
Strand: 1
Band:
Gene start: 6624802
Gene end: 6634043
  
Corresponding Affymetrix probe sets: Gga.3369.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043889
NCBI entrez gene - 395459     See in Manteia.
RefSeq - XM_015297253
RefSeq - NM_204717
RefSeq - XM_015297251
RefSeq - XM_015297252
RefSeq - XM_015297250
RefSeq Peptide - NP_990048
swissprot - Q9DGN6
Ensembl - ENSGALG00000031343
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ece1ENSDARG00000061737Danio rerio
 ECE1ENSG00000117298Homo sapiens
 Ece1ENSMUSG00000057530Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ECE2* / O60344* / EEF1AKMT4-ECE2* / EEF1AKMT4-ECE2 readthrough* / endothelin converting enzyme 2*ENSGALG0000000627266
MMEL1 / membrane metalloendopeptidase like 1 / Q495T6* / membrane metallo-endopeptidase-like 1*ENSGALG0000000111537
MME / membrane metalloendopeptidase / P08473* / Q61391* / Neprilysin *ENSGALG0000001033136
PHEX / phosphate-regulating neutral endopeptidase / P78562* / P70669* / Metalloendopeptidase homolog PEX * / phosphate regulating endopeptidase homolog X-linked*ENSGALG0000001637534
KEL / Kell blood group, metallo-endopeptidase / P23276* / Q9EQF2* / Kell blood group glycoprotein homolog *ENSGALG0000001473624
ECEL1* / O95672* / Q9JMI0* / endothelin converting enzyme like 1*ENSGALG0000003042022
ECEL1* / O95672* / Q9JMI0* / endothelin converting enzyme like 1*ENSGALG0000000787510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000718  Peptidase M13
 IPR008753  Peptidase M13, N-terminal domain
 IPR018497  Peptidase M13, C-terminal domain
 IPR024079  Metallopeptidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001921 positive regulation of receptor recycling IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0010814 substance P catabolic process IEA
 biological_processGO:0010815 bradykinin catabolic process IEA
 biological_processGO:0010816 calcitonin catabolic process IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0016486 peptide hormone processing IEA
 biological_processGO:0034959 endothelin maturation IEA
 biological_processGO:0042447 hormone catabolic process IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0043583 ear development IEA
 biological_processGO:0060037 pharyngeal system development IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0033093 Weibel-Palade body IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000012735 EDN1 / endothelin 1 / P05305* / P22387* / Endothelin-1 Big endothelin-1*  / reaction






 

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