MP:0000040 | absent middle ear ossicles | "missing small bones of the tympanic cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0000273 | overriding aorta | "congenitally mispositioned aorta where the origin straddles the ventral septum and so receives ejected blood from the right ventricle as well as the left." [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:67826] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0000274 | enlarged heart | "increase over normal size of the heart" [J:29971] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0000284 | double outlet right ventricle | "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh,Ece2tm1Ywa/Ece2tm1Ywa Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0000285 | abnormal cardiac valve morphology | "malformation of the membranous folds of the heart that prevent reflux of fluid" [J:18048] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh,Ece2tm1Ywa/Ece2tm1Ywa Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0000299 | failure of endocardial cushion closure | "failure of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal to fuse to form the valves between the right and left atrioventricular orifices" [J:29971] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh,Ece2tm1Ywa/Ece2tm1Ywa Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0000301 | reduced size of endocardial cushions | "smaller than normal mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:29973] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0000460 | mandible hypoplasia | "arrested growth or atrophy of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
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Allelic Composition: Zfp36tm1Pjb/Zfp36tm1Pjb Genetic Background: B6.Cg-Zfp36tm1Pjb
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MP:0001048 | absent enteric neurons | "missing neurons that innervate the esophagus, stomach, small and large bowel" [Principles of Neural Science:ISBN 0-8385-8034-3, J:49471] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0001613 | abnormal vasodilation | "anomalous widening of the lumen of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0002127 | abnormal cardiovascular system morphology | "abnormal development of the heart or vascular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zfp36tm1Pjb/Zfp36tm1Pjb Genetic Background: B6.Cg-Zfp36tm1Pjb
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh,Ece2tm1Ywa/Ece2tm1Ywa Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0002177 | abnormal outer ear morphology | "malformation or malfunction of any components of the auricles or external acoustic meatus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zfp36tm1Pjb/Zfp36tm1Pjb Genetic Background: B6.Cg-Zfp36tm1Pjb
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MP:0002191 | abnormal artery morphology | "malformation of the blood vessels that carry blood away from the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Junbtm3Wag/Junbtm3Wag,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002192 | hydrops fetalis | "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0002633 | persistent truncus arteriosis | "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh,Ece2tm1Ywa/Ece2tm1Ywa Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0002745 | abnormal atrioventricular valve morphology | "malformation of the valves that gate the flow of blood from the atria into the ventricles" [J:82728, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh,Ece2tm1Ywa/Ece2tm1Ywa Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0003138 | absent tympanic ring | "missing the bony ring at the ear canal to which the tympanic membrane is attached" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:46972] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0003494 | parathyroid hypoplasia | |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0003499 | thyroid hypoplasia | |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0003798 | abnormal Harderian gland pigmentation | "anomalous coloring of the sebaceous gland located behind the eyeball in the orbit that excretes fluid that facilitates movement of the third eyelid" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0004157 | interrupted aortic arch | "complete discontinuation/blockage between the ascending and descending aorta; includes Type A, interruption distal to the subclavian artery that is ipsilateral to the second carotid artery, and Type B, interruption between second carotid artery and ipsilateral subclavian artery" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0004159 | double aortic arch | "defect in which the main aorta tube splits into large left and right branches (right and left aortic arches), encircling the trachea and esophagus, before becoming one tube to go to the lower body " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
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MP:0004204 | absent stapes | "absence of the smallest and innermost of the three auditory ossicles" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0004318 | absent incus | "absence of the middle of the three auditory ossicles" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0004319 | absent malleus | "absence of the largest of the three auditory ossicles, which resembles a club or hammer" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0004423 | abnormal squamosal bone morphology | "any structural anomaly of the thin, platelike part of the temporal bone" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0004439 | absent Meckel s cartilage | "absence of this cartilage bar in the mandibular arch that forms a temporary supporting structure in the embryonic mandible; gives rise to middle ear bones and sphenomandibular and anterior malleolar ligaments" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0004460 | alisphenoid bone hypoplasia | "underdevelopment or reduced size in either of the broad curved wing like expanses on each side of the sphenoid bone in adults, usually due to reduced cell number; this bone may exist independently in the young" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0004475 | palatine bone hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, in either of two irregularly shaped bones that form the back of the hard palate and helps to form the nasal cavity and the floor of the orbits" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0004592 | small mandible | "reduced size of the lower bony framework of the mouth where the inferior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0005312 | pericardial effusion | "escape of fluid from blood vessels or lymphatics into the fibrous sac surrounding the heart" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh,Ece2tm1Ywa/Ece2tm1Ywa Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0006354 | abnormal fourth branchial arch artery morphology | "any structural anomaly of the vessels formed within the fourth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
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MP:0006355 | abnormal sixth branchial arch artery morphology | "any structural anomaly of the vessels formed within the sixth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
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MP:0006356 | abnormal third branchial arch artery morphology | "any structural anomaly of the vessels formed within the third pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
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MP:0008023 | abnormal styloid process morphology | "any structural abnormality in the slender needle-like pointed projection that runs downward and slightly forward from the base of the inferior surface of the petrous portion of the temporal bone where it joins the tympanic portion; it gives attachment to the styloglossus, stylohyoid, and stylopharyngeus muscles and the stylohyoid and stylomandibular ligaments" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0009388 | abnormal epidermal melanocyte morphology | "any structural anomaly of the cells that produce pigment in the epidermis" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0009525 | abnormal submandibular duct morphology | "any strucutral anomaly of the duct of the submadibular gland that opens at the sublingual papilla near the frenulum of the tongue" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0009707 | absent external auditory canal | "absence of the canal that connects the outer and middle ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0009867 | abnormal ascending aorta morphology | "any structural anomaly of the portion of the aorta that arises from the base of the left ventricle and extends upward to the aortic arch and from which the coronary arteries arise" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
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MP:0009905 | absent tongue | "absence of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0010191 | abnormal choroid melanocyte morphology | "any structural anomaly of the cells that produce pigment in the choroid" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0010402 | ventricular septal defect | "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0010418 | perimembraneous ventricular septal defect | "abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh,Ece2tm1Ywa/Ece2tm1Ywa Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0010426 | abnormal heart and great artery attachment | "any anomaly in the in the position or pattern of the connection site of the heart to any of the great arteries, including the pulmonary artery and aorta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0010465 | aberrant origin of the right subclavian artery | "the right subclavian artery arises from an atypical location on the aortic arch or the proximal descending aorta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
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MP:0010486 | absent right subclavian artery | "absence of one of the two subclavian arteries; the right subclavian artery normally extends from the brachiocephalic artery to the right side of the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0010572 | persistent right dorsal aorta | "persistence of the right dorsal aorta after development; the right dorsal aorta normally regresses but when it persists, a double aortic arch develops; if the left dorsal aorta also regresses, a right aortic arch forms" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
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MP:0010720 | absent sublingual duct | "absence of the canals that drain the sublingual gland" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0010722 | persistent cervical thymus | "the solid lobe of the thymus fails to descend to the mediastinum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh,Ece2tm1Ywa/Ece2tm1Ywa Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0011108 | partial embryonic lethality during organogenesis | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac
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MP:0012310 | persistent ductus caroticus | "uni- or bilateral persistence of the segment of dorsal aorta located between the third (III) and fourth (IV) aortic arches, which normally regresses early in development; persistence of ductus caroticus with regression of third arch or fourth arch causes the internal and external carotid arteries to arise from the aortic arch on the left side" [MGI:anna] |
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Allelic Composition: Ece1tm1Reh/Ece1tm1Reh Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
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MP:0030122 | temporal bone squamous part hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the anterosuperior portion of the temporal bone that is thin, scale-like, and translucent and forms part of the lateral wall of the cranial vault" [MGI:anna] |
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Allelic Composition: Ccnd1tm1Wbg/Ccnd1tm1Wbg,Ccnd3tm1Pisc/Ccnd3tm1Pisc Genetic Background: Not Specified
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