| MP:0000026 | abnormal inner ear morphology | "malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
Show
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0000031 | abnormal cochlea morphology | "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484] |
Show
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0000039 | abnormal otic capsule morphology | "malformation of the cartilage or bony capsule surrounding the inner ear mechanism" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: B6.C-PhexHyp-Duk/J
|
| MP:0000043 | organ of Corti degeneration | "a retrogressive impairment of function or destruction of the highly specialized epithelium in the floor of the ductus cochlearis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0000062 | increased bone density | "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
Show
Allelic Composition: Fgf23tm1Sliu/Fgf23+,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
|
| MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexHpr/Y
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0000088 | short mandible | "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
|
| MP:0000091 | short premaxilla | "reduced length of the anterior and interior portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370] |
Show
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
|
| MP:0000097 | short maxilla | "reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0000130 | abnormal cancellous bone morphology | "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
|
| MP:0000133 | abnormal long bone metaphysis morphology | "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295] |
Show
Allelic Composition: Fgf23tm1Blan/Fgf23tm1Blan,PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
|
| MP:0000135 | reduced cortical bone thickness | "thinner than normal superficial layer of compact bone " [J:61509] |
Show
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
|
| MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Leprdb/Lepr+,Tg(APPswe,PSEN1dE9)85Dbo/0
Genetic Background: involves: C3H * C57BL/6 * C57BLKS/J
Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
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Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0000165 | abnormal hypertrophic chondrocyte zone | "anomaly of the cartilage cell matrix layer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795] |
Show
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
|
| MP:0000195 | hypocalcemia | "subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0000198 | hypophosphatemia | "abnormally low concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Fgf23tm1Sliu/Fgf23+,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexHyp/Y
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexHyp/Phex+
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: Phextm1.1Mkd/Y,Tg(BGLAP-cre)1Clem/0
Genetic Background: B6.Cg-Phextm1.1Mkd Tg(BGLAP-cre)1Clem
Allelic Composition: Phextm1.2Mkd/Y
Genetic Background: B6.129-Phextm1.2Mkd
Allelic Composition: PhexHyp/?
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexHyp/Phex+,Tg(Bglap2-Phex)1Ldq/?
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C3H/HeSnJ * C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C3H/HeSnJ * C57BL/6J
Allelic Composition: PhexMhdabap012/PhexMhdabap012
Genetic Background: C3HeB/FeJ-PhexMhdabap012
Allelic Composition: PhexMhdabap024/PhexMhdabap024
Genetic Background: C3HeB/FeJ-PhexMhdabap024
Allelic Composition: PhexHpr/Y
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Runx1tm1Spe/Runx1+
Genetic Background: either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
|
| MP:0000440 | domed skull | |
Show
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
|
| MP:0000547 | short limbs | "reduced average length of the extremities" [MGI:CLS, J:61509] |
Show
Allelic Composition: Mtortm1.1Seq/Mtortm1.2Seq,Tg(Nphs2-cre)1Seq/?
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
| MP:0000556 | abnormal hindlimb morphology | "malformation of the entire posterior extremities" [MGI:tc] |
Show
Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-2J/Phex+
Genetic Background: C57BL/6-PhexHyp-2J/J
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp-Duk/Phex+
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: PhexHyp/Phex+
Genetic Background: C57BL/6J
Allelic Composition: PhexPug/Phex+
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0000559 | abnormal femur morphology | "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Fgf23tm1Blan/Fgf23tm1Blan,PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: Fgf23tm1Sliu/Fgf23+,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
|
| MP:0000592 | short tail | "reduced length of tail compared to control " [J:55583] |
Show
Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-2J/Phex+
Genetic Background: C57BL/6-PhexHyp-2J/J
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp-Duk/Phex+
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: PhexHyp/Phex+
Genetic Background: C57BL/6J
Allelic Composition: PhexPug/Phex+
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
|
| MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: Fgf23tm1Sliu/Fgf23+,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Runx1tm1Spe/Runx1+
Genetic Background: either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)
Allelic Composition: PhexPug/Phex+
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexMhdabap024/PhexMhdabap024
Genetic Background: C3HeB/FeJ-PhexMhdabap024
Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0001394 | circling | "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295] |
Show
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp-Duk/Phex+
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexMhdabap012/PhexMhdabap012
Genetic Background: C3HeB/FeJ-PhexMhdabap012
Allelic Composition: PhexMhdabap024/PhexMhdabap024
Genetic Background: C3HeB/FeJ-PhexMhdabap024
|
| MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
Show
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0001410 | head bobbing | "compulsive up and down movement of the head" [J:17123] |
Show
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0001541 | abnormal osteoclast function | "reduced ability or inability of osteoclasts to absorb and remove osseous tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795] |
Show
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
|
| MP:0001562 | abnormal circulating calcium level | "anomalous concentration in the blood of this bivalent element" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
|
| MP:0001565 | abnormal circulating phosphate level | "anomalous blood concentrations of this salt or ester of phosphoric acid; often associated with anomalous bone mineralization " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
|
| MP:0001566 | hyperphosphatemia | "abnormally high concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Fgf23tm1Blan/Fgf23tm1Blan,PhexHyp/Y
Genetic Background: Not Specified
|
| MP:0001666 | abnormal nutrient absorption | "anomalous ability of the body to take in constituents of food necessary for normal physiologic function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: PhexHyp/Phex+
Genetic Background: C57BL/6J
Allelic Composition: PhexHyp/Y
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C3H/HeSnJ * C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C3H/HeSnJ * C57BL/6J
|
| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp-Duk/Phex+
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0001849 | ear inflammation | "local accumulation of fluid, plasma proteins and leukocytes in the ear" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0001850 | otitis media | "middle ear inflammation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60896] |
Show
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
|
| MP:0002089 | abnormal postnatal growth/weight/body size | "increased or decreased average body size, weight or growth characteristic abnormalities manifesting after birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp/Phex+
Genetic Background: C57BL/6J
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
|
| MP:0002115 | abnormal skeleton extremities morphology | "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0002116 | abnormal craniofacial bone morphology | "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0002427 | dwarfism | "abnormally undersized with disproportionate body parts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: PhexPug/Phex+
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
|
| MP:0002759 | abnormal caudal vertebrae morphology | "malformed bony segments of the tail, usually 27-30 present" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:82849] |
Show
Allelic Composition: PhexHyp/Y
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexHyp/Phex+
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0002764 | short tibia | " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0002765 | short fibula | "reduced length of the lateral and smaller of bone of the lower leg" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:12736] |
Show
Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0002835 | abnormal cranial suture morphology | "defects of the fibrous joint in the bones of the head" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:62161] |
Show
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
|
| MP:0002857 | cochlear ganglion degeneration | "loss of neural cell bodies in the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0002896 | abnormal bone mineralization | "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Fgf23tm1Blan/Fgf23tm1Blan,PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/Phex+,Tg(Bglap2-Phex)1Ldq/?
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
|
| MP:0002901 | hyperphosphaturia | "an increase of excretion of phosphates in the urine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6
|
| MP:0002905 | decreased circulating parathyroid hormone level | "less than expected blood concentration of this regulator of calcium and phosphorous concentration" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
|
| MP:0002932 | abnormal joint | "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0002966 | decreased circulating alkaline phosphatase level | "reduced activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: PhexMhdabap024/PhexMhdabap024
Genetic Background: C3HeB/FeJ-PhexMhdabap024
|
| MP:0002968 | increased circulating alkaline phosphatase level | "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6
Allelic Composition: PhexMhdabap012/PhexMhdabap012
Genetic Background: C3HeB/FeJ-PhexMhdabap012
Allelic Composition: PhexHpr/Y
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0003055 | abnormal epiphyseal plate morphology | "malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0003109 | short femur | "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: Fgf23tm1Blan/Fgf23+,PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: Phextm1.1Mkd/Y,Tg(BGLAP-cre)1Clem/0
Genetic Background: B6.Cg-Phextm1.1Mkd Tg(BGLAP-cre)1Clem
Allelic Composition: Phextm1.2Mkd/Y
Genetic Background: B6.129-Phextm1.2Mkd
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexHpr/Y
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0003116 | rickets | "overproduction and deficient calcification of osteoid tissue due to vitamin D deficiency; can lead to skeletal deformities, growth defects, hypocalcemia, and sometimes tetany; skeletal fractures occur frequently" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Fgf23tm1Sliu/Fgf23+,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexHyp/?
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/Phex+,Tg(Bglap2-Phex)1Ldq/?
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
|
| MP:0003167 | abnormal scala tympani morphology | "any malformation or absence of the division of the spiral canal of the cochlea lying on the basal side of the spiral lamina" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:56294] |
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Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0003408 | increased width of hypertrophic chondrocyte zone | "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: PhexHyp/?
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
|
| MP:0003662 | abnormal proliferative zone | "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254] |
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Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0003718 | maternal effect | "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: PhexHyp/PhexHyp
Genetic Background: B6.Cg-PhexHyp/J
|
| MP:0003723 | abnormal long bone morphology | "malformation of any of the several elongated bones of the extremities
" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0003795 | abnormal bone structure | |
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Allelic Composition: PhexHpr/Y
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0003797 | abnormal compact bone morphology | "structural anomaly of the outer layers of solid, hard bone that covers spongy bone; consists of parallel osteons containing mineral deposits and interstitial lamellae" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator] |
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Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0004016 | decreased bone mass | "a reduction in the total amount of bone tissue contained in the skeleton" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: PhexHyp/Phex+,Tg(Bglap2-Phex)1Ldq/?
Genetic Background: involves: C57BL/6J
|
| MP:0004338 | small clavicle | "reduced size of one or both of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0004348 | long femur | "increased length of the long bone of the thigh" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Fgf23tm1Blan/Fgf23tm1Blan,PhexHyp/Y
Genetic Background: Not Specified
|
| MP:0004351 | short humerus | "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0004355 | short radius | "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0004359 | short ulna | "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0004380 | short frontal bone | "reduced length of the bone forming the forehead and roof of the eye orbit" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
|
| MP:0004471 | short nasal bone | "reduced length of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
|
| MP:0004509 | abnormal pelvic girdle bone morphology | "any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0004610 | small vertebrae | "reduced size of the bony segments of the spinal column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0004652 | small caudal vertebrae | "reduced size of the bony segments of the coccyx or tail; there are usually 27-30 present in rodents and only 3-5 fused vertebrae in human" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: PhexHyp/Y
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexHyp/Phex+
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: B6.Cg-PhexHyp/J
|
| MP:0004686 | decreased length of long bones | "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: Phextm1.1Mkd/Y,Tg(BGLAP-cre)1Clem/0
Genetic Background: B6.Cg-Phextm1.1Mkd Tg(BGLAP-cre)1Clem
Allelic Composition: Phextm1.2Mkd/Y
Genetic Background: B6.129-Phextm1.2Mkd
Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0004699 | unilateral deafness | "bilateral asymmetry in auditory function whereby one of the two ears displays auditory thresholds indicative of intact hearing while the other ear displays thresholds reflecting auditory dysfunction " [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0004993 | decreased bone resorption | "reduced amount of degradation of the organic and inorganic phases of bone by absorption, usually by the abnormal function or number of osteoclasts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
|
| MP:0005272 | abnormal temporal bone morphology | "anomalous structure of the large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0005352 | small skull | "less than the normal size of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0005353 | abnormal patella morphology | "anomalous structure of the large sesamoid bone that covers the anterior surface of the knee" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47316] |
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Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
|
| MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0005628 | decreased circulating potassium level | "less than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission] |
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Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
|
| MP:0006025 | distended Reissner membrane | "an increase in the volume of endolymphatic fluid that results in distortion of the vestibular membrane" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0006089 | abnormal saccule morphology | "malformation in the smaller of the two sacs in the vestibule" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, J:92940] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0006325 | impaired hearing | "reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0006397 | disorganized long bone epiphyseal plate | "a lack of the regular arrangement of the cells or zones of the epiphyseal plate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
|
| MP:0006398 | increased long bone epiphyseal plate size | "greater than the normal size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0006431 | abnormal fibrocartilage morphology | "any structural anomaly of the nonvascular, resilient, flexible connective tissue containing thick bundles of collagenous fibers; found primarily in intervertebral disks" [ISBN:0-8036-0655-9 "Taber s Cyclopedic Medical Dictionary", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexHyp/?
Genetic Background: involves: C57BL/6J
|
| MP:0008151 | increased diameter of long bones | "increased width of the cross-sectional distance that extends from one lateral edge of a long bone, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lepob/Lepob,Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
|
| MP:0008152 | decreased diameter of femur | "reduced width of the cross-sectional distance that extends from one lateral edge of the femur, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgf23tm1Blan/Fgf23tm1Blan,PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0008158 | increased diameter of femur | "increased width of the cross-sectional distance that extends from one lateral edge of the femur, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgf23tm1Blan/Fgf23+,PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexHpr/Y
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0008525 | decreased skull height | "decrease in the distance between the cranial base and the upper domelike portion of the skull" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
|
| MP:0009445 | osteomalacia | "gradual softening and bending of the bones due to failure of osteoid tissue to calcify as a result of vitamin D deficiency or renal tubular dysfunction" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: PhexHyp/Y
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexHyp/Phex+
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: Phextm1.1Mkd/Y,Tg(BGLAP-cre)1Clem/0
Genetic Background: B6.Cg-Phextm1.1Mkd Tg(BGLAP-cre)1Clem
Allelic Composition: Phextm1.2Mkd/Y
Genetic Background: B6.129-Phextm1.2Mkd
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: B6.Cg-PhexHyp/J
Allelic Composition: PhexHyp/Phex+,Tg(Bglap2-Phex)1Ldq/?
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
|
| MP:0009780 | abnormal chondrocyte physiology | "any functional anomaly of nondividing cartilage cells" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: PhexHyp/?
Genetic Background: involves: C57BL/6J
|
| MP:0009877 | exostosis | "a projection of bone, sometimes a benign tumor, that is capped by cartilage and arises from a bone that develops from cartilage" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
|
| MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
|
| MP:0010110 | abnormal renal phosphate reabsorption | "any anomaly in the process by which phosphate (salt or ester of phosphoric acid) is transported out of the renal tubules back into the bloodstream" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: Phextm1.1Mkd/Y,Tg(BGLAP-cre)1Clem/0
Genetic Background: B6.Cg-Phextm1.1Mkd Tg(BGLAP-cre)1Clem
Allelic Composition: Phextm1.2Mkd/Y
Genetic Background: B6.129-Phextm1.2Mkd
|
| MP:0010124 | decreased bone mineral content | "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
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| MP:0010924 | abnormal osteoid morphology | "any structural anomaly of newly formed organic bone matrix secreted by osteoblasts, that exists prior to calcification; it is comprised mainly of type I collagen fibers, chondroitin sulfate and osteocalcin" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Phexm1Jrt/Y
Genetic Background: B6.129S1-PhexM1Jrt
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| MP:0011221 | decreased intestinal calcium absorption | "reduced ability of the body to take up calcium into the blood by absorption from the small intestine" [MGI:csmith] |
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Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6J
Allelic Composition: PhexHyp/PhexHyp
Genetic Background: involves: C57BL/6J
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| MP:0011228 | abnormal vitamin D level | "any anomaly in the concentration of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism; specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)" [GO:0042368] |
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Allelic Composition: Fgf23tm1Sliu/Fgf23+,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Fgf23tm1Sliu/Fgf23tm1Sliu,PhexHyp/Y
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
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| MP:0011447 | abnormal renal glucose reabsorption | "any anomaly in the process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron" [GO:0035623] |
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Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6
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| MP:0011476 | abnormal urine nucleotide level | "any change in the urinary level of glycosamines consisting of a nucleobase, a five-carbon sugar moiety (ribose or deoxyribose), and may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates)" [MGI:csmith] |
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Allelic Composition: PhexHyp/Y
Genetic Background: involves: C57BL/6
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| MP:0011504 | abnormal limb long bone morphology | |
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Allelic Composition: PhexSka1/PhexSka1
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Phex+
Genetic Background: C57BL/6-PhexSka1
Allelic Composition: PhexSka1/Y
Genetic Background: C57BL/6-PhexSka1
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| MP:0011505 | camptomelia | "a skeletal dysplasia characterized by the bending of the long bones of the extremities" [ISBN:0-683-40008-8] |
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Allelic Composition: Phexm1Jrt/Phex+
Genetic Background: B6.129S1-PhexM1Jrt
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| MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
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Allelic Composition: PhexHyp-Duk/Y
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
Allelic Composition: PhexHyp-Duk/Y
Genetic Background: B6.C-PhexHyp-Duk/J
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| MP:0013942 | enthesitis | "inflammation of the entheses, the sites where tendons or ligaments insert into the bone; the entheses are any point of attachment of skeletal muscles to the bone, where recurring stress or inflammatory autoimmune disease can cause inflammation or occasionally fibrosis and calcification" [https://en.wikipedia.org/wiki/Enthesitis] |
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Allelic Composition: PhexHyp/?
Genetic Background: involves: C57BL/6J
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| MP:0014104 | decreased chondrocyte apoptosis | "reduced number of chondrocytes undergoing programmed cell death" [MGI:csmith] |
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Allelic Composition: PhexPug/Y
Genetic Background: involves: C57BL/6J
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| MP:0020137 | decreased bone mineralization | "decrease in the rate at which minerals are deposited into bone" [] |
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Allelic Composition: PhexHyp/Y
Genetic Background: C57BL/6J
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| MP:0030484 | abnormal osteocyte lacuna morphology | "any structural anomaly of the small cavity within the bone matrix that is occupied by an osteocyte cell body, and from which slender canaliculi radiate and penetrate the adjacent lamellae to anastomose with the canaliculi of neighboring lacunae, thus forming a system of cavities interconnected by minute canals" [https://medical-dictionary.thefreedictionary.com/osteocyte+lacuna] |
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Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: Phextm1.1Mkd/Y,Tg(BGLAP-cre)1Clem/0
Genetic Background: B6.Cg-Phextm1.1Mkd Tg(BGLAP-cre)1Clem
Allelic Composition: Phextm1.2Mkd/Y
Genetic Background: B6.129-Phextm1.2Mkd
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| MP:0030485 | abnormal osteocyte lacunocanalicular system morphology | "any structural anomaly of the large network intercommunicating the lacunae and canaliculi which contain the osteocytes and their cytoplasmic processes within the mineralized bone matrix" [PMID:22928392] |
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Allelic Composition: PhexHyp/Y
Genetic Background: Not Specified
Allelic Composition: Phextm1.1Mkd/Y,Tg(BGLAP-cre)1Clem/0
Genetic Background: B6.Cg-Phextm1.1Mkd Tg(BGLAP-cre)1Clem
Allelic Composition: Phextm1.2Mkd/Y
Genetic Background: B6.129-Phextm1.2Mkd
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