ENSGALG00000031841


Gallus gallus

Features
Gene ID: ENSGALG00000031841
  
Biological name :SLX4
  
Synonyms : SLX4 / SLX4 structure-specific endonuclease subunit
  
Possible biological names infered from orthology : Q6P1D7 / Q8IY92 / Structure-specific endonuclease subunit SLX4
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 12490400
Gene end: 12514687
  
Corresponding Affymetrix probe sets: Gga.10421.1.S1_s_at (Chicken Array)   Gga.16089.1.S1_s_at (Chicken Array)   Gga.18816.1.S1_at (Chicken Array)   GgaAffx.22308.1.S1_at (Chicken Array)   GgaAffx.22308.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048258
NCBI entrez gene - 416665     See in Manteia.
RefSeq - XM_015294629
RefSeq - XM_015294630
RefSeq - XM_015294631
RefSeq - XM_015294632
RefSeq - XM_015294633
RefSeq - XM_004945379
swissprot - A0A1D5P6D3
Ensembl - ENSGALG00000031841
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-44g23.2ENSDARG00000092927Danio rerio
 slx4ENSDARG00000061414Danio rerio
 SLX4ENSG00000188827Homo sapiens
 Slx4ENSMUSG00000039738Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR018574  Structure-specific endonuclease subunit Slx4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0010792 DNA double-strand break processing involved in repair via single-strand annealing IEA
 biological_processGO:0061820 telomeric D-loop disassembly IEA
 biological_processGO:0072429 response to intra-S DNA damage checkpoint signaling IEA
 biological_processGO:0090656 t-circle formation IEA
 biological_processGO:1904357 negative regulation of telomere maintenance via telomere lengthening IEA
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0033557 Slx1-Slx4 complex IEA
 cellular_componentGO:0048476 Holliday junction resolvase complex IEA
 cellular_componentGO:0070522 ERCC4-ERCC1 complex IEA
 molecular_functionGO:0008047 enzyme activator activity IEA
 molecular_functionGO:0008821 crossover junction endodeoxyribonuclease activity IEA
 molecular_functionGO:0017108 5"-flap endonuclease activity IEA
 molecular_functionGO:0048257 3"-flap endonuclease activity IEA


Pathways (from Reactome)
Pathway description
Resolution of D-loop Structures through Holliday Junction Intermediates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000040380 RAD51C / RAD51 paralog C / O43502* / Q924H5* / DNA repair 3 *  / reaction
 ENSGALG00000011533 XRCC3 / X-ray repair cross complementing 3 / O43542* / Q9CXE6* / X-ray repair complementing defective repair in Chinese hamster cells 3*  / reaction






 

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