ENSGALG00000032506


Gallus gallus

Features
Gene ID: ENSGALG00000032506
  
Biological name :GEM
  
Synonyms : GEM / GTP-binding protein GEM
  
Possible biological names infered from orthology : GTP binding protein overexpressed in skeletal muscle / P55040 / P55041
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 126585920
Gene end: 126594298
  
Corresponding Affymetrix probe sets: Gga.14455.1.S1_at (Chicken Array)   Gga.14455.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052355
NCBI entrez gene - 404771     See in Manteia.
RefSeq - NM_213579
RefSeq Peptide - NP_998744
swissprot - A0A1D5PHS5
Ensembl - ENSGALG00000032506
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gemENSDARG00000029112Danio rerio
 GEMENSG00000164949Homo sapiens
 GemENSMUSG00000028214Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRAD / GTP-binding protein RAD / P55042* / Ras-related associated with diabetes* / RRAD, Ras related glycolysis inhibitor and calcium channel regulator*ENSGALG0000000514062
REM1 / RRAD and GEM like GTPase 1 / O35929* / O75628* / GTP-binding protein REM 1 *ENSGALG0000004560253
MRAS / muscle RAS oncogene homolog / O08989* / O14807* / muscle and microspikes RAS*ENSGALG0000001159222
RALB / RAS like proto-oncogene B / P11234* / Q9JIW9* / Ras-related protein Ral-B *ENSGALG0000002649322
RALA / RAS like proto-oncogene A / P11233* / P63321* / Ras-related protein Ral-A *ENSGALG0000003189322
RRAS2 / RAS related 2 / P62070* / P62071* / Ras-related protein R-Ras2 *ENSGALG0000000599821
RASL11A / RAS like family 11 member A / Q6IMB1* / Q6T310* / Ras-like protein family member 11A *ENSGALG0000001709920
KRAS / KRAS proto-oncogene, GTPase / P01116* / P32883* / GTPase KRas GTPase KRas, N-terminally processed*ENSGALG0000003094320
RASL12 / RAS like family 12 / Q08AT1* / Q9NYN1* / Ras-like protein family member 12 *ENSGALG0000000734920
RERG / RAS like estrogen regulated growth inhibitor / Q8R367* / Q96A58* / Ras-related and estrogen-regulated growth inhibitor *ENSGALG0000002818619
NRAS / GTPase NRas precursor / P01111* / neuroblastoma ras oncogene* / NRAS proto-oncogene, GTPase*ENSGALG0000002669219
ENSGALG0000000771019
H-RAS / P08642 / GTPase HRas GTPase HRas, N-terminally processed / HRAS* / Q61411* / P01112* / HRas proto-oncogene, GTPase*ENSGALG0000003452618
RERGL / RERG like / Q9H628* / RERG/RAS-like*ENSGALG0000001311218
H-RAS / P08642 / GTPase HRas GTPase HRas, N-terminally processed / HRAS* / Q61411* / P01112* / HRas proto-oncogene, GTPase*ENSGALG0000002926018
RASL11B / RAS like family 11 member B / Q922H7* / Q9BPW5* / Ras-like protein family member 11B *ENSGALG0000001394818
ENSGALG0000002777816


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR017358  Ras-related small G protein, RGK family
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0051276 chromosome organization IEA
 biological_processGO:0051310 metaphase plate congression IEA
 biological_processGO:1901842 negative regulation of high voltage-gated calcium channel activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0051233 spindle midzone IEA
 cellular_componentGO:0072686 mitotic spindle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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