ENSGALG00000032534


Gallus gallus

Features
Gene ID: ENSGALG00000032534
  
Biological name :OBSCN
  
Synonyms : OBSCN / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  
Possible biological names infered from orthology : Q5VST9
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 2110152
Gene end: 2290343
  
Corresponding Affymetrix probe sets: Gga.11373.1.S1_s_at (Chicken Array)   Gga.13635.1.S1_s_at (Chicken Array)   Gga.18045.1.S1_s_at (Chicken Array)   GgaAffx.26302.1.S1_at (Chicken Array)   GgaAffx.26305.1.S1_at (Chicken Array)   GgaAffx.26305.2.S1_s_at (Chicken Array)   GgaAffx.26305.3.S1_at (Chicken Array)   GgaAffx.2949.1.S1_at (Chicken Array)   GgaAffx.2951.1.S1_at (Chicken Array)   GgaAffx.2951.1.S1_x_at (Chicken Array)   GgaAffx.2953.1.S1_s_at (Chicken Array)   GgaAffx.2953.2.S1_s_at (Chicken Array)   GgaAffx.3316.1.S1_at (Chicken Array)   GgaAffx.3317.1.S1_at (Chicken Array)   GgaAffx.3330.1.S1_at (Chicken Array)   GgaAffx.3330.2.S1_at (Chicken Array)   GgaAffx.3330.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049405
NCBI entrez gene - 420395     See in Manteia.
RefSeq - XM_015281113
swissprot - A0A1D5P9K1
Ensembl - ENSGALG00000032534
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 obscnbENSDARG00000022101Danio rerio
 OBSCNENSG00000154358Homo sapiens
 ObscnENSMUSG00000061462Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HMCN1 / hemicentin 1 / D3YXG0* / Q96RW7*ENSGALG0000003112910
OBSL1 / obscurin like 1 / D3YYU8* / O75147* / Obscurin-like protein 1 *ENSGALG000000112428
MXRA5 / matrix remodeling associated 5 / Q9NR99*ENSGALG000000166354
ENSGALG000000090894
ENSGALG000000325504
IGSF10 / immunoglobulin superfamily member 10 / Q3V1M1* / Q6WRI0*ENSGALG000000442934
MYPN / myopalladin / Q5DTJ9* / Q86TC9*ENSGALG000000039252
ENSGALG000000318261
ENSGALG000000308941
PALLD / palladin, cytoskeletal associated protein / Q8WX93* / Q9ET54* / Palladin *ENSGALG000000096501
ENSGALG000000348920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000219  Dbl homology (DH) domain
 IPR000719  Protein kinase domain
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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