ENSGALG00000032850


Gallus gallus

Features
Gene ID: ENSGALG00000032850
  
Biological name :STK3
  
Synonyms : serine/threonine-protein kinase 3 / STK3
  
Possible biological names infered from orthology : Mus musculus serine/threonine kinase 3 (Stk3), transcript variant 2, mRNA. / Q13188 / Q9JI10 / serine/threonine kinase 3
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 128247245
Gene end: 128376565
  
Corresponding Affymetrix probe sets: Gga.12683.1.S1_at (Chicken Array)   GgaAffx.10202.1.S1_at (Chicken Array)   GgaAffx.11240.1.S1_at (Chicken Array)   GgaAffx.8921.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049566
Ensembl peptide - ENSGALP00000052760
NCBI entrez gene - 425375     See in Manteia.
RefSeq - NM_001031337
RefSeq Peptide - NP_001026508
swissprot - A0A1D5PIX3
swissprot - A0A1D5PA08
Ensembl - ENSGALG00000032850
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk3ENSDARG00000011312Danio rerio
 STK3ENSG00000104375Homo sapiens
 Stk3ENSMUSG00000022329Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STK4 / serine/threonine-protein kinase 4 / Q13043* / Q9JI11* / serine/threonine kinase 4*ENSGALG0000000409878
STK25 / serine/threonine-protein kinase 25 / O00506* / Q9Z2W1* / serine/threonine kinase 25*ENSGALG0000003773936
STK26 / serine/threonine kinase 26 / Q99JT2* / Q9P289*ENSGALG0000000604936
STK24 / serine/threonine kinase 24 / Q99KH8* / Q9Y6E0*ENSGALG0000001688528


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011524  SARAH domain
 IPR017441  Protein kinase, ATP binding site
 IPR024205  Mst1 SARAH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001841 neural tube formation IEA
 biological_processGO:0003157 endocardium development IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007417 central nervous system development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0035329 hippo signaling IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0046621 negative regulation of organ growth IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0060215 primitive hemopoiesis IEA
 biological_processGO:0060706 cell differentiation involved in embryonic placenta development IEA
 biological_processGO:0060800 regulation of cell differentiation involved in embryonic placenta development IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0097284 hepatocyte apoptotic process IEA
 biological_processGO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Signaling by Hippo


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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