ENSGALG00000033469


Gallus gallus

Features
Gene ID: ENSGALG00000033469
  
Biological name :KDM1A
  
Synonyms : KDM1A / lysine demethylase 1A
  
Possible biological names infered from orthology : Mus musculus lysine (K)-specific demethylase 1A (Kdm1a), transcript variant 3, mRNA. / O60341 / Q6ZQ88
  
Species: Gallus gallus
  
Chr. number: 23
Strand: -1
Band:
Gene start: 1719983
Gene end: 1747069
  
Corresponding Affymetrix probe sets: Gga.8775.1.S1_at (Chicken Array)   GgaAffx.20329.1.S1_s_at (Chicken Array)   GgaAffx.22296.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048449
NCBI entrez gene - 419571     See in Manteia.
RefSeq - XM_015297587
RefSeq - XM_417719
swissprot - A0A1D5P6W8
Ensembl - ENSGALG00000033469
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kdm1aENSDARG00000060679Danio rerio
 KDM1AENSG00000004487Homo sapiens
 Kdm1aENSMUSG00000036940Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KDM1B / lysine demethylase 1B / Q8CIG3* / Q8NB78* / Lysine-specific histone demethylase 1B *ENSGALG0000001268526
PAOX / polyamine oxidase / Q6QHF9* / Q8C0L6* / Mus musculus polyamine oxidase (exo-N4-amino) (Paox), transcript variant 2, mRNA.*ENSGALG0000000355716
SMOX / spermine oxidase / Q99K82* / Q9NWM0*ENSGALG0000001597715


Protein motifs (from Interpro)
Interpro ID Name
 IPR002937  Amine oxidase
 IPR007526  SWIRM domain
 IPR009057  Homeobox-like domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR017366  Histone lysine-specific demethylase
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006482 protein demethylation IEA
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0033169 histone H3-K9 demethylation IEA
 biological_processGO:0033184 positive regulation of histone ubiquitination IEA
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0034720 histone H3-K4 demethylation IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071480 cellular response to gamma radiation IEA
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
 biological_processGO:1903827 regulation of cellular protein localization IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:1990391 DNA repair complex IEA
 molecular_functionGO:0002039 p53 binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IEA
 molecular_functionGO:0032451 demethylase activity IEA
 molecular_functionGO:0032452 histone demethylase activity IEA
 molecular_functionGO:0032453 histone demethylase activity (H3-K4 specific) IEA
 molecular_functionGO:0032454 histone demethylase activity (H3-K9 specific) IEA
 molecular_functionGO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) IEA
 molecular_functionGO:0042162 telomeric DNA binding IEA
 molecular_functionGO:0043426 MRF binding IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0050681 androgen receptor binding IEA
 molecular_functionGO:0061752 telomeric repeat-containing RNA binding IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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