ENSGALG00000033709


Gallus gallus

Features
Gene ID: ENSGALG00000033709
  
Biological name :LTA4H
  
Synonyms : leukotriene A-4 hydrolase / LTA4H
  
Possible biological names infered from orthology : P09960 / P24527
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 45694933
Gene end: 45718500
  
Corresponding Affymetrix probe sets: Gga.11612.1.S1_s_at (Chicken Array)   GgaAffx.20728.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046693
Ensembl peptide - ENSGALP00000059226
Ensembl peptide - ENSGALP00000050341
Ensembl peptide - ENSGALP00000049711
Ensembl peptide - ENSGALP00000049704
Ensembl peptide - ENSGALP00000045703
NCBI entrez gene - 417918     See in Manteia.
RefSeq - NM_001006234
RefSeq Peptide - NP_001006234
swissprot - A0A1L1RKF2
swissprot - A0A1D5PC56
swissprot - A0A1D5PAE8
swissprot - A0A1D5NZ88
Ensembl - ENSGALG00000033709
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lta4hENSDARG00000006029Danio rerio
 LTA4HENSG00000111144Homo sapiens
 Lta4hENSMUSG00000015889Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RNPEP / arginyl aminopeptidase / Q8VCT3* / Q9H4A4* / arginyl aminopeptidase (aminopeptidase B)*ENSGALG0000000037435
RNPEPL1 / arginyl aminopeptidase like 1 / G5E872* / Q9HAU8* / Aminopeptidase RNPEPL1 *ENSGALG0000000832111
C9orf3* / Q8N6M6* / 2010111I01Rik* / chromosome 9 open reading frame 3*ENSGALG000000407969
C9orf3* / Q8N6M6* / 2010111I01Rik* / chromosome 9 open reading frame 3*ENSGALG000000413437
C9orf3* / Q8N6M6* / 2010111I01Rik* / chromosome 9 open reading frame 3*ENSGALG000000360576


Protein motifs (from Interpro)
Interpro ID Name
 IPR001930  Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
 IPR012777  Leukotriene A4 hydrolase
 IPR014782  Peptidase M1, membrane alanine aminopeptidase, N-terminal
 IPR015211  Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0019370 leukotriene biosynthetic process IEA
 biological_processGO:0043171 peptide catabolic process IEA
 biological_processGO:0044267 cellular protein metabolic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0004301 epoxide hydrolase activity IEA
 molecular_functionGO:0004463 leukotriene-A4 hydrolase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Neutrophil degranulation
Biosynthesis of D-series resolvins
Biosynthesis of protectins
Biosynthesis of E-series 18(S)-resolvins
Biosynthesis of aspirin-triggered D-series resolvins
Biosynthesis of E-series 18(R)-resolvins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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