ENSGALG00000034461


Gallus gallus

Features
Gene ID: ENSGALG00000034461
  
Biological name :TOPBP1
  
Synonyms : DNA topoisomerase II binding protein 1 / TOPBP1
  
Possible biological names infered from orthology : DNA topoisomerase 2-binding protein 1 / Q6ZQF0 / Q92547
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 42796996
Gene end: 42828794
  
Corresponding Affymetrix probe sets: Gga.11098.1.S1_s_at (Chicken Array)   GgaAffx.23635.1.S1_at (Chicken Array)   GgaAffx.23637.1.S1_at (Chicken Array)   GgaAffx.7463.1.S1_at (Chicken Array)   GgaAffx.7464.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047284
Ensembl peptide - ENSGALP00000056114
NCBI entrez gene - 420694     See in Manteia.
RefSeq - XM_015281750
RefSeq - XM_015281749
swissprot - A0A1D5PT72
swissprot - A0A1D5P3M9
Ensembl - ENSGALG00000034461
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 topbp1ENSDARG00000059322Danio rerio
 Q92547ENSG00000163781Homo sapiens
 Q6ZQF0ENSMUSG00000032555Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ECT2* / Q07139* / Q9H8V3* / Protein ECT2 * / epithelial cell transforming 2*ENSGALG0000000915711


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR016126  Secretoglobin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010212 response to ionizing radiation IEA
 cellular_componentGO:0000794 condensed nuclear chromosome IEA
 cellular_componentGO:0001673 male germ cell nucleus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0016605 PML body IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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