ENSGALG00000034610


Gallus gallus

Features
Gene ID: ENSGALG00000034610
  
Biological name :ARFGEF1
  
Synonyms : ADP ribosylation factor guanine nucleotide exchange factor 1 / ARFGEF1
  
Possible biological names infered from orthology : Brefeldin A-inhibited guanine nucleotide-exchange protein 1 / G3X9K3 / Q9Y6D6
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 115785451
Gene end: 115869427
  
Corresponding Affymetrix probe sets: Gga.5263.1.S1_a_at (Chicken Array)   Gga.5263.3.S1_s_at (Chicken Array)   GgaAffx.24709.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048426
NCBI entrez gene - 420170     See in Manteia.
RefSeq - XM_418283
swissprot - A0A1D5P6U6
Ensembl - ENSGALG00000034610
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arfgef1ENSDARG00000063474Danio rerio
 Q9Y6D6ENSG00000066777Homo sapiens
 G3X9K3ENSMUSG00000067851Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000000466374
IQSEC3 / IQ motif and Sec7 domain 3 / Q3TES0* / Q9UPP2* / IQ motif and SEC7 domain-containing protein 3 *ENSGALG0000001297510
CYTH1 / cytohesin 1 / Q15438* / Q9QX11*ENSGALG000000070939
CYTH3* / O08967* / O43739* / cytohesin 3*ENSGALG000000071499
IQSEC1 / IQ motif and Sec7 domain 1 / Q6DN90* / Q8R0S2* / IQ motif and SEC7 domain-containing protein 1 *ENSGALG000000050429
CYTH4 / cytohesin-4 / Q80YW0* / Q9UIA0*ENSGALG000000124548
FBXO8 / F-box protein 8 / Q9NRD0* / Q9QZN3* / F-box only protein 8 *ENSGALG000000107644
ENSGALG000000441641


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR011989  Armadillo-like helical
 IPR015403  Sec7, C-terminal
 IPR016024  Armadillo-type fold
 IPR023394  Sec7, C-terminal domain superfamily
 IPR032629  Mon2, dimerisation and cyclophilin-binding domain
 IPR032691  Guanine nucleotide exchange factor, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0010256 endomembrane system organization IEA
 biological_processGO:0030837 negative regulation of actin filament polymerization IEA
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0090284 positive regulation of protein glycosylation in Golgi IEA
 biological_processGO:0090303 positive regulation of wound healing IEA
 biological_processGO:2000114 regulation of establishment of cell polarity IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030532 small nuclear ribonucleoprotein complex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017022 myosin binding IEA
 molecular_functionGO:0034237 protein kinase A regulatory subunit binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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