ENSDARG00000063474


Danio rerio

Features
Gene ID: ENSDARG00000063474
  
Biological name :arfgef1
  
Synonyms : ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) / arfgef1
  
Possible biological names infered from orthology : ADP ribosylation factor guanine nucleotide exchange factor 1 / Brefeldin A-inhibited guanine nucleotide-exchange protein 1 / G3X9K3 / Q9Y6D6
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 18736916
Gene end: 18877118
  
Corresponding Affymetrix probe sets: Dr.11803.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000126540
Ensembl peptide - ENSDARP00000087215
Ensembl peptide - ENSDARP00000150827
NCBI entrez gene - 100329953     See in Manteia.
RefSeq - XM_009297398
RefSeq - XM_009297397
RefSeq - XM_009297399
swissprot - K7DYL1
swissprot - E7FGL2
ZFIN ID - ZDB-GENE-030131-108
Ensembl - ENSDARG00000063474
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000004663Gallus gallus
 ARFGEF1ENSGALG00000034610Gallus gallus
 Q9Y6D6ENSG00000066777Homo sapiens
 G3X9K3ENSMUSG00000067851Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arfgef2 / ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)ENSDARG0000007470272
iqsec1b / IQ motif and Sec7 domain 1b / Q8R0S2* / IQSEC1* / Q6DN90* / IQ motif and Sec7 domain 1* / IQ motif and SEC7 domain-containing protein 1 *ENSDARG0000001655111
iqsec2a / IQ motif and Sec7 domain 2a / IQSEC2* / Q5JU85* / IQ motif and Sec7 domain 2*ENSDARG0000010212511
iqsec3a / IQ motif and Sec7 domain 3a / Q9UPP2* / IQSEC3* / Q3TES0* / IQ motif and Sec7 domain 3* / IQ motif and SEC7 domain-containing protein 3 *ENSDARG0000009985010
LO017700.1 / IQSEC1* / Q6DN90* / IQ motif and Sec7 domain 1*ENSDARG0000007382210
iqsec2b / IQ motif and Sec7 domain 2b / IQSEC2* / Q5JU85* / IQ motif and Sec7 domain 2*ENSDARG0000007770910
iqsec3b / IQ motif and Sec7 domain 3b / Q9UPP2* / IQSEC3* / Q3TES0* / IQ motif and Sec7 domain 3* / IQ motif and SEC7 domain-containing protein 3 *ENSDARG000000930919
cyth1b / cytohesin 1b / CYTH1* / Q15438* / Q9QX11* / cytohesin 1*ENSDARG000000214888
CYTH2 / si:dkey-283b15.4 / P63034* / Q99418* / AC008403.1* / cytohesin 2*ENSDARG000000288008
cyth4a / cytohesin 4a / CYTH4* / Q80YW0* / Q9UIA0* / cytohesin 4*ENSDARG000000380118
cyth1a / cyth3b / cytohesin 1a / CYTH3* / O43739* / cytohesin 3*ENSDARG000000051598
cyth1a / cytohesin 1a / CYTH1* / Q15438* / cytohesin 1*ENSDARG000000767428
cyth3a / cytohesin 3a / CYTH3* / O08967* / O43739* / cytohesin 3*ENSDARG000000078078
cyth4b / cytohesin 4b / CYTH4* / Q80YW0* / Q9UIA0* / cytohesin 4*ENSDARG000001039847
fbxo8 / F-box protein 8 / Q9NRD0* / Q9QZN3* / F-box only protein 8 *ENSDARG000000074774
si:ch211-189a21.1 / CYTH3* / O08967* / O43739* / cytohesin 3*ENSDARG000000898293


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR011989  Armadillo-like helical
 IPR015403  Sec7, C-terminal
 IPR016024  Armadillo-type fold
 IPR023394  Sec7, C-terminal domain superfamily
 IPR032629  Mon2, dimerisation and cyclophilin-binding domain
 IPR032691  Guanine nucleotide exchange factor, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016192 vesicle-mediated transport IBA
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005802 trans-Golgi network IBA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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