ENSDARG00000077709


Danio rerio

Features
Gene ID: ENSDARG00000077709
  
Biological name :iqsec2b
  
Synonyms : IQ motif and Sec7 domain 2b / iqsec2b
  
Possible biological names infered from orthology : IQ motif and Sec7 domain 2 / IQSEC2 / Q5JU85
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 36803415
Gene end: 36978659
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000119031
Ensembl peptide - ENSDARP00000100804
Ensembl peptide - ENSDARP00000150625
NCBI entrez gene - 797187     See in Manteia.
swissprot - E9QDV4
swissprot - F1R952
ZFIN ID - ZDB-GENE-081105-73
Ensembl - ENSDARG00000077709
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IQSEC2ENSG00000124313Homo sapiens
 Iqsec2ENSMUSG00000041115Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
iqsec2a / IQ motif and Sec7 domain 2a / IQSEC2* / Q5JU85* / IQ motif and Sec7 domain 2*ENSDARG0000010212571
iqsec1b / IQ motif and Sec7 domain 1b / Q8R0S2* / IQSEC1* / Q6DN90* / IQ motif and Sec7 domain 1* / IQ motif and SEC7 domain-containing protein 1 *ENSDARG0000001655143
LO017700.1 / IQSEC1* / Q6DN90* / IQ motif and Sec7 domain 1*ENSDARG0000007382234
iqsec3a / IQ motif and Sec7 domain 3a / Q9UPP2* / IQSEC3* / Q3TES0* / IQ motif and Sec7 domain 3* / IQ motif and SEC7 domain-containing protein 3 *ENSDARG0000009985026
iqsec3b / IQ motif and Sec7 domain 3b / Q9UPP2* / IQSEC3* / Q3TES0* / IQ motif and Sec7 domain 3* / IQ motif and SEC7 domain-containing protein 3 *ENSDARG0000009309123
arfgef1 / ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) / G3X9K3* / Q9Y6D6* / Brefeldin A-inhibited guanine nucleotide-exchange protein 1 * / ADP ribo...ENSDARG0000006347412
arfgef2 / ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)ENSDARG0000007470212
CYTH2 / si:dkey-283b15.4 / P63034* / Q99418* / AC008403.1* / cytohesin 2*ENSDARG000000288007
cyth1a / cyth3b / cytohesin 1a / CYTH3* / O43739* / cytohesin 3*ENSDARG000000051597
cyth1b / cytohesin 1b / CYTH1* / Q15438* / Q9QX11* / cytohesin 1*ENSDARG000000214887
cyth4a / cytohesin 4a / CYTH4* / Q80YW0* / Q9UIA0* / cytohesin 4*ENSDARG000000380117
cyth3a / cytohesin 3a / CYTH3* / O08967* / O43739* / cytohesin 3*ENSDARG000000078077
cyth4b / cytohesin 4b / CYTH4* / Q80YW0* / Q9UIA0* / cytohesin 4*ENSDARG000001039847
cyth1a / cytohesin 1a / CYTH1* / Q15438* / cytohesin 1*ENSDARG000000767427
fbxo8 / F-box protein 8 / Q9NRD0* / Q9QZN3* / F-box only protein 8 *ENSDARG000000074776
si:ch211-189a21.1 / CYTH3* / O08967* / O43739* / cytohesin 3*ENSDARG000000898293


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000904  Sec7 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR033742  IQ motif and SEC7 domain-containing protein, PH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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