ENSDARG00000102125


Danio rerio

Features
Gene ID: ENSDARG00000102125
  
Biological name :iqsec2a
  
Synonyms : IQ motif and Sec7 domain 2a / iqsec2a
  
Possible biological names infered from orthology : IQ motif and Sec7 domain 2 / IQSEC2 / Q5JU85
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 22567363
Gene end: 22739757
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000156791
Ensembl peptide - ENSDARP00000157331
Ensembl peptide - ENSDARP00000141504
Ensembl peptide - ENSDARP00000147502
Ensembl peptide - ENSDARP00000147771
Ensembl peptide - ENSDARP00000149810
Ensembl peptide - ENSDARP00000151263
NCBI entrez gene - 560461     See in Manteia.
swissprot - A0A0G2L9N5
ZFIN ID - ZDB-GENE-170302-3
Ensembl - ENSDARG00000102125
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IQSEC2ENSG00000124313Homo sapiens
 Iqsec2ENSMUSG00000041115Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
iqsec2b / IQ motif and Sec7 domain 2b / IQSEC2* / Q5JU85* / IQ motif and Sec7 domain 2*ENSDARG0000007770966
iqsec1b / IQ motif and Sec7 domain 1b / Q8R0S2* / IQSEC1* / Q6DN90* / IQ motif and Sec7 domain 1* / IQ motif and SEC7 domain-containing protein 1 *ENSDARG0000001655140
LO017700.1 / IQSEC1* / Q6DN90* / IQ motif and Sec7 domain 1*ENSDARG0000007382232
iqsec3a / IQ motif and Sec7 domain 3a / Q9UPP2* / IQSEC3* / Q3TES0* / IQ motif and Sec7 domain 3* / IQ motif and SEC7 domain-containing protein 3 *ENSDARG0000009985024
iqsec3b / IQ motif and Sec7 domain 3b / Q9UPP2* / IQSEC3* / Q3TES0* / IQ motif and Sec7 domain 3* / IQ motif and SEC7 domain-containing protein 3 *ENSDARG0000009309121
arfgef1 / ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) / G3X9K3* / Q9Y6D6* / Brefeldin A-inhibited guanine nucleotide-exchange protein 1 * / ADP ribo...ENSDARG0000006347412
arfgef2 / ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)ENSDARG0000007470212
CYTH2 / si:dkey-283b15.4 / P63034* / Q99418* / AC008403.1* / cytohesin 2*ENSDARG000000288007
cyth1a / cyth3b / cytohesin 1a / CYTH3* / O43739* / cytohesin 3*ENSDARG000000051597
cyth1b / cytohesin 1b / CYTH1* / Q15438* / Q9QX11* / cytohesin 1*ENSDARG000000214887
cyth4a / cytohesin 4a / CYTH4* / Q80YW0* / Q9UIA0* / cytohesin 4*ENSDARG000000380117
cyth1a / cytohesin 1a / CYTH1* / Q15438* / cytohesin 1*ENSDARG000000767427
cyth3a / cytohesin 3a / CYTH3* / O08967* / O43739* / cytohesin 3*ENSDARG000000078076
cyth4b / cytohesin 4b / CYTH4* / Q80YW0* / Q9UIA0* / cytohesin 4*ENSDARG000001039846
fbxo8 / F-box protein 8 / Q9NRD0* / Q9QZN3* / F-box only protein 8 *ENSDARG000000074775
si:ch211-189a21.1 / CYTH3* / O08967* / O43739* / cytohesin 3*ENSDARG000000898293


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000904  Sec7 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR033742  IQ motif and SEC7 domain-containing protein, PH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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