ENSMUSG00000041115


Mus musculus

Features
Gene ID: ENSMUSG00000041115
  
Biological name :Iqsec2
  
Synonyms : IQ motif and Sec7 domain 2 / Iqsec2
  
Possible biological names infered from orthology : Q5JU85
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: F3
Gene start: 152144268
Gene end: 152225236
  
Corresponding Affymetrix probe sets: 10602625 (MoGene1.0st)   1436622_at (Mouse Genome 430 2.0 Array)   1444621_at (Mouse Genome 430 2.0 Array)   1448063_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108223
Ensembl peptide - ENSMUSP00000127249
Ensembl peptide - ENSMUSP00000108224
Ensembl peptide - ENSMUSP00000093995
NCBI entrez gene - 245666     See in Manteia.
MGI - MGI:3528396
RefSeq - XM_006528848
RefSeq - XM_006528842
RefSeq - XM_006528843
RefSeq - XM_006528844
RefSeq - XM_006528845
RefSeq - XM_006528846
RefSeq - XM_006528847
RefSeq - NM_001005475
RefSeq - NM_001114664
RefSeq Peptide - NP_001108136
RefSeq Peptide - NP_001005475
swissprot - E9QAD8
swissprot - D3Z6V7
swissprot - D3Z5I6
swissprot - A4GZ26
Ensembl - ENSMUSG00000041115
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 iqsec2aENSDARG00000102125Danio rerio
 iqsec2bENSDARG00000077709Danio rerio
 IQSEC2ENSG00000124313Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Iqsec1 / Q8R0S2 / IQ motif and SEC7 domain-containing protein 1 / Q6DN90* / IQ motif and Sec7 domain 1*ENSMUSG0000003431244
Iqsec3 / Q3TES0 / IQ motif and SEC7 domain-containing protein 3 / Q9UPP2* / IQ motif and Sec7 domain 3*ENSMUSG0000004079729
A2A5R2 / Arfgef2 / Brefeldin A-inhibited guanine nucleotide-exchange protein 2 / Q9Y6D5* / ADP ribosylation factor guanine nucleotide exchange factor 2*ENSMUSG0000007458213
G3X9K3 / Arfgef1 / Brefeldin A-inhibited guanine nucleotide-exchange protein 1 / Q9Y6D6* / ADP ribosylation factor guanine nucleotide exchange factor 1*ENSMUSG0000006785113
Cyth2 / P63034 / Cytohesin-2 / Q99418*ENSMUSG000000032698
Cyth3 / O08967 / Cytohesin-3 / O43739*ENSMUSG000000180018
Cyth4 / Q80YW0 / Cytohesin-4 / Q9UIA0*ENSMUSG000000180087
Cyth1 / Q9QX11 / Cytohesin-1 / Q15438*ENSMUSG000000171327
Fbxo8 / Q9QZN3 / F-box only protein 8 / Q9NRD0* / F-box protein 8*ENSMUSG000000382066


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000904  Sec7 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR033742  IQ motif and SEC7 domain-containing protein, PH domain
 IPR035999  Sec7 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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