ENSMUSG00000018001


Mus musculus

Features
Gene ID: ENSMUSG00000018001
  
Biological name :Cyth3
  
Synonyms : Cyth3 / Cytohesin-3 / O08967
  
Possible biological names infered from orthology : O43739
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 143622447
Gene end: 143710250
  
Corresponding Affymetrix probe sets: 10527233 (MoGene1.0st)   1418758_a_at (Mouse Genome 430 2.0 Array)   1431707_a_at (Mouse Genome 430 2.0 Array)   1446268_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106355
Ensembl peptide - ENSMUSP00000118290
Ensembl peptide - ENSMUSP00000135287
Ensembl peptide - ENSMUSP00000135548
Ensembl peptide - ENSMUSP00000112157
NCBI entrez gene - 19159     See in Manteia.
MGI - MGI:1335107
RefSeq - XM_017320729
RefSeq - NM_001163548
RefSeq - NM_011182
RefSeq Peptide - NP_035312
RefSeq Peptide - NP_001157020
swissprot - A0A0G2JDC7
swissprot - O08967
swissprot - G5E8Q4
swissprot - D3YXU3
swissprot - H3BK81
swissprot - Q3TXK1
Ensembl - ENSMUSG00000018001
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyth1aENSDARG00000005159Danio rerio
 cyth3aENSDARG00000007807Danio rerio
 si:ch211-189a21.1ENSDARG00000089829Danio rerio
 ENSGALG00000007149Gallus gallus
 CYTH3ENSG00000008256Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyth1 / Q9QX11 / Cytohesin-1 / Q15438*ENSMUSG0000001713282
Cyth2 / P63034 / Cytohesin-2 / Q99418*ENSMUSG0000000326979
Cyth4 / Q80YW0 / Cytohesin-4 / Q9UIA0*ENSMUSG0000001800870
G3X9K3 / Arfgef1 / Brefeldin A-inhibited guanine nucleotide-exchange protein 1 / Q9Y6D6* / ADP ribosylation factor guanine nucleotide exchange factor 1*ENSMUSG0000006785140
A2A5R2 / Arfgef2 / Brefeldin A-inhibited guanine nucleotide-exchange protein 2 / Q9Y6D5* / ADP ribosylation factor guanine nucleotide exchange factor 2*ENSMUSG0000007458240
Iqsec1 / Q8R0S2 / IQ motif and SEC7 domain-containing protein 1 / Q6DN90* / IQ motif and Sec7 domain 1*ENSMUSG0000003431230
Iqsec3 / Q3TES0 / IQ motif and SEC7 domain-containing protein 3 / Q9UPP2* / IQ motif and Sec7 domain 3*ENSMUSG0000004079729
Iqsec2 / IQ motif and Sec7 domain 2 / Q5JU85*ENSMUSG0000004111528
Fbxo8 / Q9QZN3 / F-box only protein 8 / Q9NRD0* / F-box protein 8*ENSMUSG0000003820615


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR035999  Sec7 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0045785 positive regulation of cell adhesion IDA
 biological_processGO:0048193 Golgi vesicle transport IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0090162 establishment of epithelial cell polarity IMP
 cellular_componentGO:0001726 ruffle IPI
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity ISS
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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