ENSGALG00000035717


Gallus gallus

Features
Gene ID: ENSGALG00000035717
  
Biological name :HSPG2
  
Synonyms : heparan sulfate proteoglycan 2 / HSPG2
  
Possible biological names infered from orthology : P98160 / perlecan (heparan sulfate proteoglycan 2)
  
Species: Gallus gallus
  
Chr. number: 21
Strand: 1
Band:
Gene start: 6549468
Gene end: 6577788
  
Corresponding Affymetrix probe sets: Gga.7471.1.S1_at (Chicken Array)   Gga.7471.2.A1_s_at (Chicken Array)   GgaAffx.1038.1.S1_at (Chicken Array)   GgaAffx.1099.1.S1_at (Chicken Array)   GgaAffx.23137.1.S1_s_at (Chicken Array)   GgaAffx.6722.1.S1_at (Chicken Array)   GgaAffx.8824.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048851
Ensembl peptide - ENSGALP00000058795
Ensembl peptide - ENSGALP00000051462
NCBI entrez gene - 429806     See in Manteia.
RefSeq - XM_015297260
swissprot - A0A1L1RJ69
swissprot - A0A1D5PF99
swissprot - A0A1D5P806
Ensembl - ENSGALG00000035717
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hspg2ENSDARG00000076564Danio rerio
 HSPG2ENSG00000142798Homo sapiens
 Hspg2ENSMUSG00000028763Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AGRN / agrin / A2ASQ1* / O00468* / Agrin Agrin N-terminal 110 kDa subunit Agrin C-terminal 110 kDa subunit Agrin C-terminal 90 kDa fragment Agrin C-terminal 22 kDa fragment*ENSGALG0000003919311
EGFLAM / EGF like, fibronectin type III and laminin G domains / Q4VBE4* / Q63HQ2* / Pikachurin *ENSGALG000000037266
ENSGALG000000312624
EYS* / Q5T1H1* / eyes shut homolog (Drosophila)*ENSGALG000000162632


Protein motifs (from Interpro)
Interpro ID Name
 IPR000034  Laminin IV
 IPR000082  SEA domain
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR002049  Laminin EGF domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013098  Immunoglobulin I-set
 IPR013106  Immunoglobulin V-set domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
A tetrasaccharide linker sequence is required for GAG synthesis
HS-GAG biosynthesis
HS-GAG degradation
Integrin cell surface interactions
Laminin interactions
Non-integrin membrane-ECM interactions
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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