ENSGALG00000035768


Gallus gallus

Features
Gene ID: ENSGALG00000035768
  
Biological name :SCAP
  
Synonyms : SCAP / SREBF chaperone
  
Possible biological names infered from orthology : Q12770 / Q6GQT6
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 870483
Gene end: 921049
  
Corresponding Affymetrix probe sets: Gga.15324.1.S1_s_at (Chicken Array)   Gga.1699.1.S1_at (Chicken Array)   Gga.17265.1.S1_at (Chicken Array)   GgaAffx.3172.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043634
NCBI entrez gene - 420380     See in Manteia.
RefSeq - XM_015281202
swissprot - Q5F3Q8
Ensembl - ENSGALG00000035768
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scapENSDARG00000018096Danio rerio
 SCAPENSG00000114650Homo sapiens
 ScapENSMUSG00000032485Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HMGCR / 3-hydroxy-3-methylglutaryl-Coenzyme A reductase / P04035* / Q01237* / 3-hydroxy-3-methylglutaryl-CoA reductase*ENSGALG0000001494812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000731  Sterol-sensing domain
 IPR030225  Sterol regulatory element-binding protein cleavage-activating protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0019217 regulation of fatty acid metabolic process IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0032933 SREBP signaling pathway IEA
 biological_processGO:0042304 regulation of fatty acid biosynthetic process IEA
 biological_processGO:0045540 regulation of cholesterol biosynthetic process IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015485 cholesterol binding IEA


Pathways (from Reactome)
Pathway description
Regulation of cholesterol biosynthesis by SREBP (SREBF)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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