ENSGALG00000035804


Gallus gallus

Features
Gene ID: ENSGALG00000035804
  
Biological name :SQSTM1
  
Synonyms : sequestosome 1 / SQSTM1
  
Possible biological names infered from orthology : Q13501 / Q64337
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 13463302
Gene end: 13467706
  
Corresponding Affymetrix probe sets: Gga.5187.1.S1_at (Chicken Array)   Gga.5187.1.S1_s_at (Chicken Array)   GgaAffx.26656.1.S1_at (Chicken Array)   GgaAffx.26656.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053754
Ensembl peptide - ENSGALP00000060740
Ensembl peptide - ENSGALP00000060243
Ensembl peptide - ENSGALP00000059131
Ensembl peptide - ENSGALP00000057749
NCBI entrez gene - 770805     See in Manteia.
RefSeq - XM_001233248
RefSeq - XM_003642062
RefSeq - XM_004944953
RefSeq - XM_004944954
swissprot - A0A1L1RPL4
swissprot - A0A1D5PLN4
swissprot - A0A1L1RN73
swissprot - A0A1L1RK43
swissprot - A0A1D5PXQ2
Ensembl - ENSGALG00000035804
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sqstm1ENSDARG00000075014Danio rerio
 Q13501ENSG00000161011Homo sapiens
 Q64337ENSMUSG00000015837Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000270  PB1 domain
 IPR000433  Zinc finger, ZZ-type
 IPR009060  UBA-like superfamily
 IPR015940  Ubiquitin-associated domain
 IPR033741  Sequestosome-1, UBA domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000423 mitophagy IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0007032 endosome organization IEA
 biological_processGO:0016236 macroautophagy IEA
 biological_processGO:0035973 aggrephagy IEA
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0044130 negative regulation of growth of symbiont in host IEA
 biological_processGO:0061635 regulation of protein complex stability IEA
 biological_processGO:0061912 selective autophagy IEA
 biological_processGO:0098780 response to mitochondrial depolarisation IEA
 biological_processGO:1900273 positive regulation of long-term synaptic potentiation IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IEA
 biological_processGO:1905719 protein localization to perinuclear region of cytoplasm IEA
 cellular_componentGO:0000407 phagophore assembly site IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016234 inclusion body IEA
 cellular_componentGO:0016235 aggresome IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0044753 amphisome IEA
 cellular_componentGO:0044754 autolysosome IEA
 cellular_componentGO:0097225 sperm midpiece IEA
 molecular_functionGO:0005080 protein kinase C binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0035255 ionotropic glutamate receptor binding IEA
 molecular_functionGO:0042169 SH2 domain binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043130 ubiquitin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
p75NTR recruits signalling complexes
NF-kB is activated and signals survival
Pink/Parkin Mediated Mitophagy
Interleukin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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