ENSGALG00000036322


Gallus gallus

Features
Gene ID: ENSGALG00000036322
  
Biological name :MED12
  
Synonyms : MED12 / mediator complex subunit 12
  
Possible biological names infered from orthology : A2AGH6 / Mediator of RNA polymerase II transcription subunit 12 / Q93074
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 2369480
Gene end: 2402949
  
Corresponding Affymetrix probe sets: Gga.18239.1.S1_s_at (Chicken Array)   Gga.2403.1.S1_at (Chicken Array)   Gga.2403.1.S1_s_at (Chicken Array)   GgaAffx.26547.1.S1_at (Chicken Array)   GgaAffx.26547.2.S1_s_at (Chicken Array)   GgaAffx.26547.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048641
Ensembl peptide - ENSGALP00000054025
Ensembl peptide - ENSGALP00000053499
NCBI entrez gene - 422210     See in Manteia.
RefSeq - XM_015278409
RefSeq - XM_015278410
RefSeq - XM_015278411
swissprot - A0A1D5PME8
swissprot - A0A1D5PKY6
swissprot - A0A1D5P7F2
Ensembl - ENSGALG00000036322
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med12ENSDARG00000103953Danio rerio
 MED12ENSG00000184634Homo sapiens
 Med12ENSMUSG00000079487Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MED12L / mediator complex subunit 12 like / Q86YW9* / Q8BQM9* / Mediator of RNA polymerase II transcription subunit 12-like protein *ENSGALG0000001037055


Protein motifs (from Interpro)
Interpro ID Name
 IPR019035  Mediator complex, subunit Med12
 IPR021989  Mediator complex, subunit Med12, catenin-binding
 IPR021990  Mediator complex, subunit Med12, LCEWAV-domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0007492 endoderm development IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0014003 oligodendrocyte development IEA
 biological_processGO:0014044 Schwann cell development IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway IEA
 biological_processGO:0030521 androgen receptor signaling pathway IEA
 biological_processGO:0036342 post-anal tail morphogenesis IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048568 embryonic organ development IEA
 biological_processGO:0048702 embryonic neurocranium morphogenesis IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060071 Wnt signaling pathway, planar cell polarity pathway IEA
 biological_processGO:0090245 axis elongation involved in somitogenesis IEA
 biological_processGO:1990403 embryonic brain development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016592 mediator complex IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003712 transcription coregulator activity IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0046966 thyroid hormone receptor binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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