ENSGALG00000037203


Gallus gallus

Features
Gene ID: ENSGALG00000037203
  
Biological name :CTNNB1
  
Synonyms : catenin beta-1 / CTNNB1
  
Possible biological names infered from orthology : P35222 / Q02248
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 43601202
Gene end: 43622660
  
Corresponding Affymetrix probe sets: Gga.4283.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045406
Ensembl peptide - ENSGALP00000061781
Ensembl peptide - ENSGALP00000061519
Ensembl peptide - ENSGALP00000061112
Ensembl peptide - ENSGALP00000059065
Ensembl peptide - ENSGALP00000055195
NCBI entrez gene - 395964     See in Manteia.
RefSeq - NM_205081
RefSeq - XM_015281298
RefSeq - XM_015281299
RefSeq Peptide - NP_990412
swissprot - A0A1D5PQN0
swissprot - A0A1L1RSJ7
swissprot - A0A1D5NYE8
swissprot - A0A1L1RRU8
swissprot - A0A1L1RQN5
swissprot - A0A1L1RK02
Ensembl - ENSGALG00000037203
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctnnb1ENSDARG00000014571Danio rerio
 CTNNB1ENSG00000168036Homo sapiens
 Ctnnb1ENSMUSG00000006932Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
JUP / junction plakoglobin / P14923* / Q02257*ENSGALG0000001741464


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR011989  Armadillo-like helical
 IPR013284  Beta-catenin
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000578 embryonic axis specification IEA
 biological_processGO:0000904 cell morphogenesis involved in differentiation IEA
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IEA
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001702 gastrulation with mouth forming second IEA
 biological_processGO:0001706 endoderm formation IEA
 biological_processGO:0001708 cell fate specification IEA
 biological_processGO:0001709 cell fate determination IEA
 biological_processGO:0001711 endodermal cell fate commitment IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001840 neural plate development IEA
 biological_processGO:0001944 vasculature development IEA
 biological_processGO:0002052 positive regulation of neuroblast proliferation IEA
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IEA
 biological_processGO:0002089 lens morphogenesis in camera-type eye IEA
 biological_processGO:0003266 regulation of secondary heart field cardioblast proliferation IEA
 biological_processGO:0003338 metanephros morphogenesis IEA
 biological_processGO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007398 ectoderm development IEA
 biological_processGO:0007403 glial cell fate determination IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009948 anterior/posterior axis specification IEA
 biological_processGO:0009950 dorsal/ventral axis specification IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IEA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0009987 cellular process IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process IEA
 biological_processGO:0016331 morphogenesis of embryonic epithelium IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0021819 layer formation in cerebral cortex IEA
 biological_processGO:0022009 central nervous system vasculogenesis IEA
 biological_processGO:0022405 hair cycle process IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030217 T cell differentiation IEA
 biological_processGO:0030316 osteoclast differentiation IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030539 male genitalia development IEA
 biological_processGO:0030856 regulation of epithelial cell differentiation IEA
 biological_processGO:0030858 positive regulation of epithelial cell differentiation IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0030902 hindbrain development IEA
 biological_processGO:0030997 regulation of centriole-centriole cohesion IEA
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0031069 hair follicle morphogenesis IEA
 biological_processGO:0031641 regulation of myelination IEA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IEA
 biological_processGO:0032331 negative regulation of chondrocyte differentiation IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0033077 T cell differentiation in thymus IEA
 biological_processGO:0033234 negative regulation of protein sumoylation IEA
 biological_processGO:0034332 adherens junction organization IEA
 biological_processGO:0034333 adherens junction assembly IEA
 biological_processGO:0034394 protein localization to cell surface IEA
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0035050 embryonic heart tube development IEA
 biological_processGO:0035112 genitalia morphogenesis IEA
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0035116 embryonic hindlimb morphogenesis IEA
 biological_processGO:0036023 embryonic skeletal limb joint morphogenesis IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042129 regulation of T cell proliferation IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0043525 positive regulation of neuron apoptotic process IEA
 biological_processGO:0043588 skin development IEA
 biological_processGO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process IEA
 biological_processGO:0045453 bone resorption IEA
 biological_processGO:0045595 regulation of cell differentiation IEA
 biological_processGO:0045596 negative regulation of cell differentiation IEA
 biological_processGO:0045603 positive regulation of endothelial cell differentiation IEA
 biological_processGO:0045667 regulation of osteoblast differentiation IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0045670 regulation of osteoclast differentiation IEA
 biological_processGO:0045671 negative regulation of osteoclast differentiation IEA
 biological_processGO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045976 negative regulation of mitotic cell cycle, embryonic IEA
 biological_processGO:0048096 chromatin-mediated maintenance of transcription IEA
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0048489 synaptic vesicle transport IEA
 biological_processGO:0048513 animal organ development IEA
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0048599 oocyte development IEA
 biological_processGO:0048617 embryonic foregut morphogenesis IEA
 biological_processGO:0048643 positive regulation of skeletal muscle tissue development IEA
 biological_processGO:0048660 regulation of smooth muscle cell proliferation IEA
 biological_processGO:0048715 negative regulation of oligodendrocyte differentiation IEA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0051145 smooth muscle cell differentiation IEA
 biological_processGO:0051884 regulation of timing of anagen IEA
 biological_processGO:0051973 positive regulation of telomerase activity IEA
 biological_processGO:0060066 oviduct development IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060173 limb development IMP
 biological_processGO:0060439 trachea morphogenesis IEA
 biological_processGO:0060440 trachea formation IEA
 biological_processGO:0060441 epithelial tube branching involved in lung morphogenesis IEA
 biological_processGO:0060479 lung cell differentiation IEA
 biological_processGO:0060484 lung-associated mesenchyme development IEA
 biological_processGO:0060492 lung induction IEA
 biological_processGO:0060742 epithelial cell differentiation involved in prostate gland development IEA
 biological_processGO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development IEA
 biological_processGO:0060789 hair follicle placode formation IEA
 biological_processGO:0060916 mesenchymal cell proliferation involved in lung development IEA
 biological_processGO:0061047 positive regulation of branching involved in lung morphogenesis IEA
 biological_processGO:0061154 endothelial tube morphogenesis IEA
 biological_processGO:0061198 fungiform papilla formation IEA
 biological_processGO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation IEA
 biological_processGO:0061549 sympathetic ganglion development IEA
 biological_processGO:0061550 cranial ganglion development IEA
 biological_processGO:0070602 regulation of centromeric sister chromatid cohesion IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 biological_processGO:0071681 cellular response to indole-3-methanol IEA
 biological_processGO:0072001 renal system development IEA
 biological_processGO:0072033 renal vesicle formation IEA
 biological_processGO:0072053 renal inner medulla development IEA
 biological_processGO:0072054 renal outer medulla development IEA
 biological_processGO:0072079 nephron tubule formation IEA
 biological_processGO:0072182 regulation of nephron tubule epithelial cell differentiation IEA
 biological_processGO:0090271 positive regulation of fibroblast growth factor production IMP
 biological_processGO:0090279 regulation of calcium ion import IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:1901215 negative regulation of neuron death IEA
 biological_processGO:1903204 negative regulation of oxidative stress-induced neuron death IEA
 biological_processGO:1904501 positive regulation of chromatin-mediated maintenance of transcription IEA
 biological_processGO:1904793 regulation of euchromatin binding IEA
 biological_processGO:1904796 regulation of core promoter binding IEA
 biological_processGO:1904798 positive regulation of core promoter binding IEA
 biological_processGO:1904888 cranial skeletal system development IEA
 biological_processGO:1904948 midbrain dopaminergic neuron differentiation IEA
 biological_processGO:1990138 neuron projection extension IEA
 biological_processGO:1990403 embryonic brain development IEA
 biological_processGO:1990791 dorsal root ganglion development IEA
 biological_processGO:2000008 regulation of protein localization to cell surface IEA
 biological_processGO:2000017 positive regulation of determination of dorsal identity IEA
 biological_processGO:2000144 positive regulation of DNA-templated transcription, initiation IEA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005719 nuclear euchromatin IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0005916 fascia adherens IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0014704 intercalated disc IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IEA
 cellular_componentGO:0016342 catenin complex IEA
 cellular_componentGO:0016600 flotillin complex IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030877 beta-catenin destruction complex IEA
 cellular_componentGO:0031253 cell projection membrane IEA
 cellular_componentGO:0031528 microvillus membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0032993 protein-DNA complex IEA
 cellular_componentGO:0034750 Scrib-APC-beta-catenin complex IEA
 cellular_componentGO:0043296 apical junction complex IEA
 cellular_componentGO:0044798 nuclear transcription factor complex IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070369 beta-catenin-TCF7L2 complex IEA
 cellular_componentGO:0071944 cell periphery IEA
 cellular_componentGO:1990907 beta-catenin-TCF complex IEA
 cellular_componentGO:1990909 Wnt signalosome IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0035257 nuclear hormone receptor binding IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0045294 alpha-catenin binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0046332 SMAD binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070411 I-SMAD binding IEA
 molecular_functionGO:0070491 repressing transcription factor binding IEA
 molecular_functionGO:0097718 disordered domain specific binding IEA


Pathways (from Reactome)
Pathway description
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
TCF dependent signaling in response to WNT
Formation of the beta-catenin:TCF transactivating complex
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
Apoptotic cleavage of cell adhesion proteins
CDO in myogenesis
Deactivation of the beta-catenin transactivating complex
Ca2+ pathway
Adherens junctions interactions
Disassembly of the destruction complex and recruitment of AXIN to the membrane
VEGFR2 mediated vascular permeability
RUNX3 regulates WNT signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr